3-Chloro-2-fluorobenzoic Acid CAS 161957-55-7
| CAS No. | 161957-55-7 |
| Molecular Formula | C7H4ClFO2 |
| Molecular Weight | 174.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Chloro-2-fluorobenzoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-Chloro-2-fluorobenzoic Acid (CAS 161957-55-7) is a high-purity analytical reference standard with the molecular formula C7H4ClFO2 and a molecular weight of 174.56 g/mol.
3-Chloro-2-fluorobenzoic Acid (C7H4ClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H4ClFO2 |
| Molecular Weight | 174.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-3-fluorobenzoic Acid (CAS 102940-86-3)
- 2-Chloro-5-fluoro-4-hydroxybenzaldehyde (CAS 1036383-27-3)
- 2-Chloro-6-fluoro-3-hydroxybenzaldehyde (CAS 1083103-41-6)
- 3-Chloro-6-fluoro-2-hydroxybenzaldehyde (CAS 1185112-08-6)
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Recommended Standards
- 4-Chloro-3-fluoro-2-hydroxybenzaldehyde (CAS 1427431-22-8)
- 6-Chloro-2-fluoro-3-hydroxybenzaldehyde (CAS 1704729-56-5)
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- 4-Chloro-5-fluoronicotinamide (CAS 1706432-64-5)
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- (S)-3-Chloro-5-(pyrrolidin-2-yl)pyridine (CAS 1213615-61-2)
- 1-(3-Fluorophenyl)-1H-imidazole-5-carboxylic acid (CAS 1439897-59-2)
- 2-(2-Chlorophenyl)isoquinoline-1,3(2H,4H)-dione (CAS 106110-71-8)
- N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester (CAS 2100306-76-9)
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