6-Nitronicotinoyl chloride CAS 60780-82-7
| CAS No. | 60780-82-7 |
| Molecular Formula | C6H3ClN2O3 |
| Molecular Weight | 186.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 6-Nitronicotinoyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
6-Nitronicotinoyl chloride (CAS 60780-82-7), molecular formula C6H3ClN2O3 and molecular weight 186.55 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 6-Nitronicotinoyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3ClN2O3 |
| Molecular Weight | 186.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 5-Nitropyridine-2-carbonyl chloride (CAS 59290-88-9)
- 6-Nitropyridine-2-carbonyl chloride (CAS 60780-83-8)
- 3-Nitroisonicotinoyl chloride (CAS 59290-83-4)
- 8-Chloropyrazolo[1,5-a][1,3,5]triazine-2,4(1H,3H)-dione (CAS 1309789-59-0)
- 1-Chloro-4-nitrobutane (CAS 41168-66-5)
- 4-((3-Chloro-4-fluorophenyl)amino)-7-ethoxy-6-nitroquinoline-3-carbonitrile hydrochloride (CAS 361162-94-9)
- Cilastatin Impurity 15 (CAS 1114-50-7)
- 7-Benzyloxy-1H-indazole-3-carbonitrile (CAS 1123169-54-9)
- 6-fluoro-1H-pyrrolo[3,2-b]pyridin-5-amine (CAS 2231676-58-5)
- 5-Oxopyrrolidine-2-carbohydrazide (CAS 94135-34-9)
- 6-(Phenylamino)nicotinaldehyde (CAS 1292370-14-9)
- Clemastine Impurity 6 Fumarate (S,S-isomer) (CAS 61826-29-7)
- 1-(Thiophen-3-yl)propan-2-amine hydrochloride (CAS 86188-25-2)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com