Lamotrigine Impurity 16 CAS 608-27-5
| CAS No. | 608-27-5 |
| Molecular Formula | C6H5Cl2N |
| Molecular Weight | 162.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Lamotrigine Impurity 16 (CAS 608-27-5, C6H5Cl2N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C6H5Cl2N, Lamotrigine Impurity 16 contains a nitrile group, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 162.02 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Lamotrigine Impurity 16 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5Cl2N |
| Molecular Weight | 162.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lamotrigine Standards
- Lamotrigine Impurity 23 (CAS 30885-95-1)
- Lamotrigine EP Impurity E (CAS 50-45-3)
- Lamotrigine Impurity 7 (CAS 31273-66-2)
- Lamotrigine Impurity 16 (CAS 2250242-15-8)
- Lamotrigine Impurity 17 (CAS 887354-37-2)
- Lamotrigine 6-(3,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine Impurity (CAS 36518-85-1)
- Lamotrigine EP Impurity B and Lamotrigine EP Impurity C (CAS 84689-20-3)
- Lamotrigine Impurity 10 (CAS 77668-43-0)
Recommended Standards
- Clonidine EP Impurity C (CAS 608-31-1)
- Phloroglucinol Dihydrate EP Impurity L (CAS 626-43-7)
- 2,5-Dichloro-4-methylpyridine 2,5-dichloro-4-methyl-pyridine 886365-00-0 (CAS 886365-00-0)
- 3,4-Dichloroaniline (CAS 95-76-1)
- Tebipenem impurity 21 (CAS CATO-C4X-134721)
- Enrofloxacin EP Impurity F (CAS 131775-99-0)
- Revefenacin Impurity 46 (CAS CATO-C4X-203146)
- 7-bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine (CAS 1269667-51-7)
- 3-Hydroxy-6-(hydroxymethyl)-2-((4-methylpiperidin-1-yl)methyl)-4H-pyran-4-one (CAS 92198-59-9)
- 2-Ethylpyridine-4-boronic Acid Pinacol Ester (CAS 741709-60-4)
- 3-(Pyridin-3-ylmethyl)-5-(pyridin-3-ylmethylene)-2-thioxothiazolidin-4-one (CAS 315692-96-7)
- N-(5-Bromo-2-methylphenyl)-2,2,2-trifluoroacetamide (CAS 338451-90-4)
- V9WU3IKN4Q 534-16-7 Silver carbonate Carbonic acid, disilver(1+) salt Carbonic acid, silver(1+) salt (1:2) Disilver carbonate EINECS 208-590-3 NSC 112223 Silver(1) carbonate Silver carbonate (2:1) Fetizon's reagent Silver(I) carbonate UNII-V9WU3IKN4Q EC 208-590-3 (CAS 534-16-7)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com