Lidocaine Hydrochloride Monohydrate CAS 6108-05-0
| CAS No. | 6108-05-0 |
| Molecular Formula | C14H22N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Lidocaine Hydrochloride Monohydrate (CAS 6108-05-0) is a high-purity analytical reference standard with the molecular formula C14H22N2OHClH2O and a molecular weight of 288.82 g/mol.
Structurally, Lidocaine Hydrochloride Monohydrate (C14H22N2OHClH2O) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 288.82 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Lidocaine Hydrochloride Monohydrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H22N2O HCl H2O |
| Molecular Weight | 288.82 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Lidocaine Standards
- Lidocaine EP Impurity J HCl (CAS 1012864-23-1)
- Lidocaine Impurity 70 HCl (CAS 101651-71-2)
- Lidocaine Impurity 57 (CAS 102878-74-0)
- Lidocaine Impurity 19 (CAS 108-69-0)
- Lidocaine EP Impurity H (CAS 1131-01-7)
- Lidocaine EP Impurity E Hydrochloride (CAS 1135231-62-7)
- Lidocaine-d10 Hydrochloride (CAS 1189959-13-4)
- Lidocaine EP Impurity D-d6 (CAS 1216698-89-3)
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