Brivudine Impurity N1 CAS 61135-36-2
| CAS No. | 61135-36-2 |
| Molecular Formula | C11H12Br2N2O5 |
| Molecular Weight | 412.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Brivudine Impurity N1 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Brivudine Impurity N1 (CAS 61135-36-2, C11H12Br2N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Brivudine Impurity N1 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 412.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Brivudine Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12Br2N2O5 |
| Molecular Weight | 412.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Brivudine Standards
Recommended Standards
- 16803-75-1 CTK4D2848 N-[(1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL]-2,2-DIBROMOACET AMIDE (CAS 16803-75-1)
- DImethyl 2,2'-((2,5-dibromo-1,4-phenylene)bis(oxy))diacetate (CAS 91395-60-7)
- Perphenazine-D8 (as Dihydrochloride) (CAS 1189961-11-2)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-cyclohexylphenyl)acetamide (CAS 329929-20-6)
- Molnupiravir Impurity 20 (CAS 2770244-32-9)
- CAS 62780-92-1 (CAS 62780-92-1)
- Daptomycin Impurity 44 (CAS CATO-C4X-137844)
- 4-Methyl-5-nitro-2,6-bis(phenylmethoxy)pyrimidine (CAS 30958-38-4)
- 5-Amino-1-(tert-butyl)-3-phenyl-1H-pyrazole-4-carbonitrile (CAS 180903-09-7)
- 2-Butoxy-6-fluorobenzoic acid (CAS 1499793-21-3)
- Glimepiride Impurity 18 (CAS 41176-69-6)
- 4,5,6,7-tetrahydro-1H-indole-4-carboxylic acid (CAS 1556028-87-5)
- 5-[(4-Chlorophenyl)sulfanyl]-4-(2,4-dichlorophenyl)-2-[5-(2,4-dichlorophenyl)-1H-pyrazol-1-yl]-1,3-thiazole (CAS 956778-57-7)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com