Brivudine Impurity 10 CAS 69304-48-9
| CAS No. | 69304-48-9 |
| Molecular Formula | C11H13IN2O5 |
| Molecular Weight | 380.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Brivudine Impurity 10 (CAS 69304-48-9, C11H13IN2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Brivudine Impurity 10 (C11H13IN2O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 380.14 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C11H13IN2O5 |
| Molecular Weight | 380.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Brivudine Standards
Recommended Standards
- Methyl 3-iodo-5-((2-methoxyethyl)amino)-4-nitrobenzoate (CAS 2853616-33-6)
- 1-(tert-Butyl)-4-iodo-5-(2,4,5-trifluorophenyl)-1H-pyrazole (CAS 1206676-75-6)
- (2-(2-((4-Fluorobenzyl)oxy)-5-(trifluoromethyl)phenyl)cyclopent-1-en-1-yl)boronic acid (CAS 612833-84-8)
- 3-(2-Fluorobenzyl)-6-iodoquinazolin-4(3H)-one (CAS 302913-41-3)
- Gadobutrol impurity 164 (CAS CATO-C4X-2120164)
- Levonorgestrel EP Impurity M (CAS 51087-61-7)
- Letermovir Impurity 75 (CAS CATO-C4X-291575)
- n-[(7-ethyl-1h-indol-3-yl)methylidene]hydroxylamine (CAS 790263-81-9)
- 5-((1H-Imidazol-2-yl)thio)-2-nitroaniline (CAS 55564-49-3)
- 6-(Difluoromethyl)-1,2-dihydro-4-hydroxy-2-oxo-3-pyridinecarbonitrile (CAS 1804712-10-4)
- Ethyl 4-amino-2-((chloromethyl)thio)thiazole-5-carboxylate (CAS 845879-10-9)
- 3-Bromo-5-(2-(trifluoromethyl)phenyl)pyridine (CAS 675589-99-8)
- Metoclopramide Impurity 34 (CAS CATO-C4X-141534)
- Immunstimulating Peptide, human (CAS 94773-24-7)
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