5-(Chloromethyl)-[1,2,4]triazolo[1,5-c]quinazoline CAS 61164-87-2
| CAS No. | 61164-87-2 |
| Molecular Formula | C10H7ClN4 |
| Molecular Weight | 218.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(Chloromethyl)-[1,2,4]triazolo[1,5-c]quinazoline.
5-(Chloromethyl)-[1,2,4]triazolo[1,5-c]quinazoline (CAS 61164-87-2), molecular formula C10H7ClN4 and molecular weight 218.64 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(Chloromethyl)-[1,2,4]triazolo[1,5-c]quinazoline (C10H7ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(Chloromethyl)-[1,2,4]triazolo[1,5-c]quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN4 |
| Molecular Weight | 218.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloromethyl Standards
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- 3-[4-(chloromethyl)-1,3-oxazol-2-yl]benzonitrile (CAS 1126634-12-5)
- methyl 4-[3-(chloromethyl)-1,2,4-oxadiazol-5-yl]butanoate (CAS 1311314-51-8)
- 2-(chloromethyl)-5-(3-methoxyoxolan-3-yl)-1,3,4-oxadiazole (CAS 1934656-91-3)
- 4-[4-(chloromethyl)-1,3-oxazol-2-yl]benzonitrile (CAS 202594-69-2)
- 4-(Chloromethyl)-6-methyl-2-phenylpyrimidine (CAS 131291-62-8)
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- 1-(Chloromethyl)-2-phenoxybenzene (CAS 5888-53-9)
Recommended Standards
- 5-(2-Chlorophenyl)-3-methylisoxazole-4-carbonitrile (CAS 62219-88-9)
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- 4-Pyrimidin-2-ylbenzoyl chloride (CAS 679806-84-9)
- 5-Amino-1-(3-chlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 51516-68-8)
- 9-[[2-Benzyloxy-1-(benzyloxymethyl)-ethoxy]-methyl]-6-chloroguanine (CAS 84222-47-9)
- 2-(2,5,6-Trichloropyridin-3-yl)acetic acid (CAS 63580-09-6)
- 2-Bromo-1-(2-methoxy-4-methylphenyl)ethan-1-one (CAS 145964-98-3)
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- 2-(2-((4-Fluorophenoxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246642-92-0)
- (R,E)-N-(4-(3-((5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)piperidine-1-carbonyl)phenyl)-4-(dimethylamino)but-2-enamide (CAS 1702809-17-3)
- Ethyl (2-methyltetrahydrofuran-2-yl)carbamate (CAS 61807-48-5)
- 1-Chloro-n-methyl-n-(1-phenylethyl)methanesulfonamide (CAS 1406684-24-9)
- 2-Chloro-n-{[2-(piperidine-1-sulfonyl)phenyl]methyl}acetamide (CAS 1087784-13-1)
- Brain Injury Derived Neurotrophic Peptide (H-3914.0001) (CAS 148330-12-5)
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