5-Hydroxy-2-methoxybenzoic acid CAS 61227-25-6
| CAS No. | 61227-25-6 |
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Hydroxy-2-methoxybenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 5-Hydroxy-2-methoxybenzoic acid (CAS 61227-25-6), a certified reference material (molecular formula C8H8O4, MW 168.15 g/mol) for analytical method development and quality control.
The molecular framework of 5-Hydroxy-2-methoxybenzoic acid (C8H8O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
Related Hydroxy Standards
- 3-Hydroxy-5,6-dimethylpyridazine-4-carboxylic acid (CAS 101861-29-4)
- 2-Hydroxy-4-(hydroxymethyl)benzoic acid (CAS 106420-93-3)
- 1-(5-Hydroxy-6-methoxypyridazin-4-yl)ethanone (CAS 106584-74-1)
- Methyl 4-Hydroxy-6-methylpyrimidine-2-carboxylate (CAS 1240600-77-4)
- (S)-2-Hydroxy-2-(4-hydroxyphenyl)acetic acid (CAS 13244-75-2)
- Methyl 2-hydroxy-2-(pyrazin-2-yl)acetate (CAS 1479997-67-5)
- Methyl 2-hydroxy-2-(pyrimidin-5-yl)acetate (CAS 1494496-35-3)
- 4-Hydroxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylic acid (CAS 1516650-68-2)
Recommended Standards
- 5-Formyl-N,N-dimethylisoxazole-3-carboxamide (CAS 220780-30-3)
- 5-Hydroxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylic acid (CAS 2384064-67-7)
- 5-Formyl-2,4-dimethoxypyrimidine (CAS 52606-02-7)
- 5-methoxy-2-Pyrazinecarboxylic acid methyl ester (CAS 38789-75-2)
- 2-Acetyl-3-oxobutanal (CAS 16690-08-7)
- 1-((4-Bromo-5-methoxy-2-methylphenyl)sulfonyl)-1H-pyrazole (CAS 944785-47-1)
- 7-Hydroxy-4-methoxy-2H-chromen-2-one (CAS 65692-17-3)
- Methyl 5-benzoyl-2-methylthiazole-4-carboxylate (CAS 920113-32-2)
- 2-Bromo-4-cyclopropoxynicotinaldehyde (CAS 1243354-77-9)
- 2-(3-hydroxyphenyl)-2-methylpropanoic acid (CAS 264879-13-2)
- (E)-4,4,5,5,6,6,6-Heptafluorohex-2-en-1-ol (CAS 679-03-8)
- 2-Acetylamino-4-chlorophenol (CAS 26488-93-7)
- (2Z)-3-[2-(2,4-Dichlorophenoxy)phenyl]-2-(3-methoxyphenyl)prop-2-enenitrile (CAS 866019-85-4)
- Semaglutide impurity 331 (CAS CATO-C4X-2226231)
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