Olanzapine Impurity 25 CAS 612503-08-9
| CAS No. | 612503-08-9 |
| Molecular Formula | C12H11N3S |
| Molecular Weight | 229.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Olanzapine Impurity 25 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Olanzapine Impurity 25 (CAS 612503-08-9, C12H11N3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Olanzapine Impurity 25 (C12H11N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11N3S |
| Molecular Weight | 229.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Olanzapine Standards
- Olanzapine Impurity 12 (CAS 873895-41-1)
- Olanzapine Impurity 29 (CAS 59591-86-5)
- Olanzapine Impurity 39 (CAS 1319722-10-5)
- Olanzapine Impurity 16 (CAS CATO-C4X-117816)
- Olanzapine Impurity 33 (CAS CATO-C4X-117833)
- Olanzapine Impurity 47 (CAS 612507-13-8)
- Olanzapine Impurity 17 (CAS CATO-C4X-117817)
- Olanzapine Impurity 29 (CAS 134801-02-8)
Recommended Standards
- Pioglitazone Impurity 19 (CAS 144809-26-7)
- 2-Mercapto-N-phenylbenzamide (CAS CATO-C3D-2773)
- Promethazine Impurity 16 (CAS CATO-C4X-141816)
- (1S)-(+)-(Camphorylsulfonyl)oxaziridine (CAS 104322-63-6)
- Amlexanox Impurity 1 (CAS CATO-C4X-21761)
- Isavuconazole Impurity 112 (CAS CATO-C4X-1236112)
- Trifluridine Related Compound A (CAS 14599-46-3)
- (Diisopropylamino)methanol (CAS 96-80-0)
- 5-(4-Methylpiperazin-1-yl)-2-nitrobenzamide (CAS 383148-04-7)
- Nebivolol EP Impurity A (CAS 1416402-13-5)
- 4-(1,2-Dimethyl-1H-indol-3-yl)-thiazol-2-ylamine (CAS 843622-17-3)
- 2-(Difluoromethyl)naphthalene-8-methanol (CAS 1261470-14-7)
- (5-Fluoro-2-(1H-pyrrol-1-yl)pyridin-4-yl)boronic acid (CAS 2225175-82-4)
- Insulin Degludec Impurity 13 (CAS CATO-C4X-215713)
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