3-Phenyl-2-(pyridin-2-yl)quinazoline-4(3H)-thione CAS 61351-63-1

Description

Compared with other compounds in its class, the molecular weight of 315.39 g/mol gives 3-Phenyl-2-(pyridin-2-yl)quinazoline-4(3H)-thione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-Phenyl-2-(pyridin-2-yl)quinazoline-4(3H)-thione (CAS 61351-63-1) is a high-purity analytical reference standard with the molecular formula C19H13N3S and a molecular weight of 315.39 g/mol.

The molecular framework of 3-Phenyl-2-(pyridin-2-yl)quinazoline-4(3H)-thione (C19H13N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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