3-Phenyl-2-(pyridin-4-yl)quinazoline-4(3H)-thione CAS 61351-67-5
| CAS No. | 61351-67-5 |
| Molecular Formula | C19H13N3S |
| Molecular Weight | 315.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Phenyl-2-(pyridin-4-yl)quinazoline-4(3H)-thione (CAS 61351-67-5) is a high-purity analytical reference standard with the molecular formula C19H13N3S and a molecular weight of 315.39 g/mol.
The molecular framework of 3-Phenyl-2-(pyridin-4-yl)quinazoline-4(3H)-thione (C19H13N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H13N3S |
| Molecular Weight | 315.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Phenyl Standards
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- (Benzyl(pyridin-3-ylmethyl)carbamothioyl)glycine (CAS 694516-61-5)
- 3-Phenyl-2-(pyridin-2-yl)quinazoline-4(3H)-thione (CAS 61351-63-1)
- Ethyl 2-((6-(pyridin-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)thio)acetate (CAS 1203011-40-8)
- Ethyl 2-((3-(pyridin-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)acetate (CAS 868968-19-8)
- Ethyl 2-((3-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)acetate (CAS 868970-34-7)
- Methyl 2-((3-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)propanoate (CAS 868970-38-1)
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Recommended Standards
- 4'-(Thiophen-2-yl)-2,2':6',2''-terpyridine (CAS 220525-65-5)
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- 4,6-Dimethyl-1-(prop-2-yn-1-yl)-3-(o-tolylsulfonyl)pyridin-2(1H)-one (CAS 477864-59-8)
- 3-Ethyl-1-((4-methoxyphenyl)sulfonyl)-1H-indole (CAS 88939-69-9)
- (R)-Mephenytoin (CAS 71140-51-7)
- (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)-phenyl)-3-(5-nitrothiophen-2-yl)acrylamide (CAS 1360614-48-7)
- 4-((4-Fluorophenoxy)methyl)benzoic acid (CAS 149288-44-8)
- N-(4-Cyclopropoxy-6-nitropyridin-3-yl)methanesulfonamide (CAS 1243401-78-6)
- 2-(Diethylamino)-5-nitrobenzoic acid (CAS 727718-14-1)
- (R)-1,2,3,4-Tetrahydronaphthalene-2-carboxylic acid (CAS 38157-15-2)
- 2,2,3,3,3-Pentafluoropropyl butyrate (CAS 950191-45-4)
- (2-Chloro-1,3-thiazol-5-yl)methyl 4-chlorobenzoate (CAS 672949-82-5)
- 1-((4-Isopropylcyclohexyl)amino)propan-2-ol (CAS 1342975-65-8)
- Mitogenic Pentapeptide (CAS 87173-03-3)
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