1-(3-Chlorophenyl)guanidine CAS 6145-41-1
| CAS No. | 6145-41-1 |
| Molecular Formula | C7H8ClN3 |
| Molecular Weight | 169.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(3-Chlorophenyl)guanidine is closely related to a nitrile group, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(3-Chlorophenyl)guanidine (CAS 6145-41-1), a certified reference material (molecular formula C7H8ClN3, MW 169.61 g/mol) for analytical method development and quality control.
1-(3-Chlorophenyl)guanidine (C7H8ClN3) contains a nitrile group, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8ClN3 |
| Molecular Weight | 169.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 2-(2-Chlorophenyl)acetamide (CAS 10268-06-1)
- (E)-[(2-Chlorophenyl)methylidene](methyl)oxidoazanium (CAS 1075226-89-9)
- N-(2-Chlorophenyl)-N-methylformamide (CAS 14924-76-6)
- 1-(2-Chlorophenyl)guanidine (CAS 24067-35-4)
- 2-(3-Chlorophenyl)acetamide (CAS 58357-84-9)
- N-(4-chlorophenyl)-N-methylformamide (CAS 26772-93-0)
- N-(2-chlorophenyl)acetamide (CAS 533-17-5)
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Recommended Standards
- 1-(2-chloropyridin-4-yl)propan-2-one (CAS 790706-85-3)
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- 1-(2-Chloro-6-methylpyridin-4-yl)ethanone (CAS 890406-52-7)
- 1-Methyl-4-phenyl-3-(thiophen-2-yl)-4,5-dihydro-1H-1,2,4-triazole-5-thione (CAS 1022482-46-7)
- 1,4-Dimethyl (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanedioate (CAS 147220-14-2)
- 7-Fluoroindoline-5-carbonitrile (CAS 2092093-99-5)
- 2-3-4-6-Tetra-O-acetyl-β-D-glucopyranosyl-Fmoc serine (CAS 118358-38-6)
- 3-Fluoro-2-methylbenzaldehyde (CAS 147624-13-3)
- Carbidopa Impurity 31 (CAS 28860-96-0)
- 4-Bromo-7-(2-hydroxypropan-2-yl)-9H-carbazole-1-carboxamide (CAS 1231893-68-7)
- N,N-Dimethyl-2,5-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxamide (CAS 2377610-14-3)
- 2,7-Diazabicyclo[4.2.0]octane (CAS 51392-74-6)
- [α-Glu](Sidechain trans-position)-Liraglutide (CAS CATO-C4X-199240)
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