Carbidopa Impurity 31 CAS 28860-96-0
| CAS No. | 28860-96-0 |
| Molecular Formula | C12H18N2O4 |
| Molecular Weight | 254.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Carbidopa Impurity 31 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Carbidopa Impurity 31 (CAS 28860-96-0) is a certified pharmaceutical impurity reference standard with the molecular formula C12H18N2O4 and a molecular weight of 254.28 g/mol.
Structurally, Carbidopa Impurity 31 (C12H18N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 254.28 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H18N2O4 |
| Molecular Weight | 254.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 2 |
Related Carbidopa Standards
- Carbidopa EP Impurity F (CAS 1458640-32-8)
- Carbidopa Impurity 19 (CAS CATO-C4X-231019)
- Carbidopa Impurity 8 (CAS 19728-71-3)
- rac-Carbidopa EP Impurity C (CAS 85933-19-3)
- Carbidopa Impurity 11 (CAS CATO-C4X-231011)
- Carbidopa Impurity 29 (CAS CATO-C4X-231029)
- Carbidopa EP Impurity C (CAS 84488-77-7)
- Carbidopa impurity 38 (CAS 2470439-16-6)
Recommended Standards
- Racemic carbidopa ethyl ester (CAS 91908-71-3)
- Baloxavir Marboxil Impurity 171 (CAS CATO-C4X-2108171)
- Cenobamate Impurity 54 (CAS 1233712-93-0)
- Tolvaptan Impurity 37 (CAS 607-86-3)
- Aprepitant impurity 47 (CAS 172673-20-0)
- Amodiaquine Impurity 3 (CAS 102391-07-1)
- Maxacalcitol Impurity 15 (CAS 215929-37-6)
- 2-Chloro-n'-(2-chlorobenzoyl)benzohydrazide (CAS 38192-13-1)
- Methyl 3-(chlorosulfonyl)-4-phenyl-5-(trifluoromethyl)thiophene-2-carboxylate (CAS 306935-98-8)
- Benzyl 2-((tert-butyldimethylsilyl)oxy)acetate (CAS 115118-86-0)
- 2-(4-ethoxyphenyl)-4-ethyl-1,3-thiazole-5-carboxylic acid (CAS 938312-70-0)
- cis-7-Amino-8-fluoro-2-aza-spiro[4.4]nonane-2-carboxylic acid tert-butyl ester (CAS 1638757-71-7)
- Ethyl 4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxylate (CAS 862546-07-4)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
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