6-Amino-2-(2-nitrophenyl)quinoline-5,8-dione CAS 61472-37-5
| CAS No. | 61472-37-5 |
| Molecular Formula | C15H9N3O4 |
| Molecular Weight | 295.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 6-Amino-2-(2-nitrophenyl)quinoline-5,8-dione (CAS 61472-37-5), a certified reference material (molecular formula C15H9N3O4, MW 295.25 g/mol) for analytical method development and quality control.
The molecular framework of 6-Amino-2-(2-nitrophenyl)quinoline-5,8-dione (C15H9N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H9N3O4 |
| Molecular Weight | 295.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 1-(4-Amino-1,2,5-oxadiazol-3-yl)-5-(morpholinomethyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 352446-60-7)
- 6-Amino-4-(2-nitrophenyl)quinoline-5,8-dione (CAS 824405-23-4)
- 7-Amino-2-(2-nitrophenyl)quinoline-5,8-dione (CAS 61472-46-6)
- Methyl 2-amino-5-[3-(trifluoromethyl)phenyl]benzoate (CAS 926236-39-7)
- 3-Amino-5-[3-(trifluoromethyl)phenyl]-1H,5H,6H-pyrazolo[4,3-c]pyridazin-6-one (CAS 338395-89-4)
- 4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-(prop-1-yn-1-yl)pyrimidin-2(1H)-one (CAS 179817-96-0)
- 2-((4-Amino-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)-N-(4-fluorophenyl)acetamide (CAS 869068-23-5)
- 7-Amino-2-(2-aminophenyl)-6-methoxyquinoline-5,8-dione (CAS 61472-30-8)
Recommended Standards
- 5,8-Dihydro-6-hydroxy-5,8-dioxo-2-phenyl-4-quinolinecarboxylic acid (CAS 24682-19-7)
- 3-(4-Nitrophenyl)-1-phenyl-1H-pyrazole-4,5-dione (CAS 60759-51-5)
- 2'-O,4'-C-Methyleneguanosine (CAS 207131-16-6)
- Ethyl (4-fluorophenyl)(hydroxy(pyridin-3-yl)methyl)phosphinate (CAS 69112-28-3)
- 2,4-Diethyl-1-Octanol (CAS 55514-25-5)
- Purpactin A (CAS 133806-59-4)
- (3-((3-Bromophenyl)sulfonamido)phenyl)boronic acid (CAS 913835-31-1)
- 3-(Furan-2-yl)-N-((1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl)methyl)acrylamide (CAS 2035001-88-6)
- (8-(6-Chloropyridazin-3-yl)-1-oxa-4,8-diazaspiro[4.5]Decan-4-yl)(4-methoxyphenyl)methanone (CAS 339011-62-0)
- 3-(Methylsulfonyl)-4-(3-nitrophenyl)-1H-pyrrole (CAS 87388-61-2)
- 2,6-Diallylphenol (CAS 3382-99-8)
- Resmetirom impurity 82 (CAS CATO-C4X-291282)
- Aprepitant impurity 52 (CAS CATO-C4X-114152)
- Immunstimulating Peptide, human (CAS 94773-24-7)
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