Resmetirom impurity 82 CAS CATO-C4X-291282
| CAS No. | CATO-C4X-291282 |
| Molecular Formula | C13H11Cl2N3O4 |
| Molecular Weight | 344.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Resmetirom impurity 82 (C13H11Cl2N3O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 344.15 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Resmetirom impurity 82 (CAS CATO-C4X-291282), a pharmacopoeial impurity reference standard (molecular formula C13H11Cl2N3O4, MW 344.15 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Resmetirom impurity 82 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H11Cl2N3O4 |
| Molecular Weight | 344.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Resmetirom Standards
- Resmetirom impurity 131 (CAS 2768216-97-1)
- Resmetirom Impurity 100 (CAS CATO-C4X-2912100)
- Resmetirom Impurity 127 (CAS CATO-C4X-2912127)
- Resmetirom Impurity 48 (CAS CATO-C4X-291248)
- Resmetirom Impurity 102 (CAS CATO-C4X-2912102)
- Resmetirom impurity 103 (CAS CATO-C4X-2912103)
- Resmetirom Impurity 30 (CAS CATO-C4X-291230)
- Resmetirom Impurity 5 (CAS 920509-27-9)
Recommended Standards
- 5-Benzoyl-2-(4-bromophenyl)-1H-1,2,4-triazol-3(2H)-one (CAS 1000574-42-4)
- Metronidazole Impurity 27 (CAS CATO-C4X-140527)
- 5-Benzoyl-2-(3-bromophenyl)-1H-1,2,4-triazol-3(2H)-one (CAS 1000575-57-4)
- Tert-butyl 5-iodo-1H-benzo[d]imidazole-1-carboxylate (CAS 705262-62-0)
- Axitinib Impurity 60 (CAS CATO-C4X-107160)
- CAS CATO-C3D-262723 (CAS CATO-C3D-262723)
- Erlotinib Impurity 64 (CAS CATO-C4X-106964)
- 5-Iodo-4,6-dimethoxy-2-(4-methylpiperazin-1-yl)pyrimidine (CAS 1268273-74-0)
- 4-(4-Thioxo-1,3,5-triazinan-1-yl)butanoic acid (CAS 247109-16-6)
- 5-Bromopyridine-2-boronic Acid (CAS 652148-97-5)
- 2-(2-Fluorophenyl)-2-methoxypropanoic acid (CAS 1247392-62-6)
- 2-(1,1-Dioxidothiomorpholino)-3-(1H-indol-3-yl)-1-(4-phenylpiperazin-1-yl)propan-1-one (CAS 478040-56-1)
- 1,2,3-Tri-O-benzyl-4,6-O-benzylidene-b-D-galactopyranose (CAS 57783-80-9)
- Semaglutide Impurity 188 (CAS CATO-C4X-2226188)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com