(R)-1-benzyl-3-hydroxypiperidin-2-one CAS 614754-32-4
| CAS No. | 614754-32-4 |
| Molecular Formula | C12H15NO2 |
| Molecular Weight | 205.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-1-benzyl-3-hydroxypiperidin-2-one.
(R)-1-benzyl-3-hydroxypiperidin-2-one (CAS 614754-32-4), molecular formula C12H15NO2 and molecular weight 205.25 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (R)-1-benzyl-3-hydroxypiperidin-2-one (C12H15NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 205.25 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-1-benzyl-3-hydroxypiperidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15NO2 |
| Molecular Weight | 205.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
Recommended Standards
- (R)-1-((S)-1-phenylethyl)azetidine-2-carboxylic acid (CAS 204274-32-8)
- (R)-1-Benzyl-pyrrolidine-3-carboxylic acid (CAS 216311-57-8)
- (R)-(+)-2-(Boc-amino)-1,4-butanediol (CAS 397246-14-9)
- (R)-2-(1,2,3,4-tetrahydroquinolin-6-yl)propanoic acid (CAS 2387562-44-7)
- tert-Butyl 4-(2-chloro-5-fluoropyrimidin-4-yl)piperazine-1-carboxylate (CAS 1338495-22-9)
- (3S,4R)-4-Amino-3-pyrrolidinemethanol (CAS 2166200-43-5)
- 1H-Pyrrolo[3,2-b]pyridine-5-acetic acid (CAS 1261578-71-5)
- 4-(1,3-Dihydro-isoindol-2-yl)-butyric acid hydrochloride (CAS 1185298-64-9)
- 2,6-Dichloro-3-(difluoromethoxy)benzyl alcohol (CAS 1803713-50-9)
- 4-Chloro-2-hydroxy-N-methoxy-N-methylbenzamide (CAS 566945-71-9)
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- 2-((2-(2-Ethoxyethoxy)ethoxy)methyl)oxirane (CAS 50522-30-0)
- C-Peptide 2 (rat) (CAS 41594-08-5)
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