1-{[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}-3-(trifluoromethyl)-1h-pyrazole CAS 1486485-54-4
| CAS No. | 1486485-54-4 |
| Molecular Formula | C17H20BF3N2O2 |
| Molecular Weight | 352.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-{[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}-3-(trifluoromethyl)-1h-pyrazole.
1-{[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}-3-(trifluoromethyl)-1h-pyrazole (CAS 1486485-54-4), molecular formula C17H20BF3N2O2 and molecular weight 352.16 g/mol, is a CATO reference standard with documented purity and traceability.
1-{[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}-3-(trifluoromethyl)-1h-pyrazole (C17H20BF3N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-{[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}-3-(trifluoromethyl)-1h-pyrazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H20BF3N2O2 |
| Molecular Weight | 352.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related tetramethyl Standards
- 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-(3-trifluoromethyl-benzyl)-1H-pyrazole (CAS 1415825-08-9)
- 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-(2-trifluoromethyl-benzyl)-1H-pyrazole (CAS 1604036-75-0)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(4-(trifluoromethyl)benzyl)-1H-pyrazole (CAS 1853185-17-7)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl trifluoromethanesulfonate (CAS 1027059-48-8)
- 3'-Methyl-4'-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-carboxylic acid methyl ester (CAS 1411993-04-8)
- N-(4-((3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amino)phenyl)acetamide (CAS 1201644-31-6)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(m-tolyl)urea (CAS 765949-02-8)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(o-tolyl)urea (CAS 935660-79-0)
Recommended Standards
- Methyl 4-((5-bromo-2-hydroxybenzylidene)amino)-3-fluorobenzoate (CAS 1296225-21-2)
- Methyl 2-(2-(3-bromo-4-fluorophenyl)acetyl)nicotinate (CAS 1036402-42-2)
- (E)-[(6-Bromo-2H-1,3-benzodioxol-5-yl)methylidene][(2-fluorophenyl)methoxy]amine (CAS 478078-92-1)
- 1,1'-biphenyl, 2,2'-bis(bromomethyl)- 2,2'-bis(bromomethyl)biphenyl 38274-14-5 InChI=1/C14H12Br2/c15-9-11-5-1-3-7-13(11)14-8-4-2-6-12(14)10-16/h1-8H,9-10H (CAS 38274-14-5)
- Benzyl (3S,4S)-3-amino-4-methylpyrrolidine-1-carboxylate (CAS 1400580-20-2)
- 2,2-Diethoxyethanethioamide (CAS 73956-15-7)
- 2-Amino-6-ethyl-N-(o-tolyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 667437-83-4)
- 2-(2,3-Dichlorophenyl)pyrimidine (CAS 95573-52-7)
- 3-Oxa-1,7,8-triazaspiro[4.4]nonane (CAS 126505-39-3)
- 1-((2,6-Dichlorophenoxy)methyl)-4-nitro-1H-pyrazole (CAS 1005612-29-2)
- 2-Chloro-1-(1-ethyl-4-nitro-1H-pyrrol-2-yl)ethanone (CAS 53391-47-2)
- (S)-2-(((Benzyloxy)carbonyl)amino)-3-fluoropropanoic acid (CAS 36369-37-6)
- Ethyl 4-[2-(methylamino)acetyl]piperazine-1-carboxylate (CAS 1073555-07-3)
- D-Thr7-Tirzepatide (CAS CATO-CPTD788924)
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