21-Dehydro Betamethasone CAS 61558-12-1
| CAS No. | 61558-12-1 |
| Molecular Formula | C22H27FO5 |
| Molecular Weight | 390.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 21-Dehydro Betamethasone (CAS 61558-12-1), a certified reference material (molecular formula C22H27FO5, MW 390.45 g/mol) for analytical method development and quality control.
21-Dehydro Betamethasone (C22H27FO5) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 21-Dehydro Betamethasone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H27FO5 |
| Molecular Weight | 390.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F-containing |
Related Dehydro Standards
- 21-Dehydro Dexamethasone (CAS 2964-79-6/4619-61-8)
- (3β)-7-Dehydro Cholesterol-d7 (CAS 388622-58-0)
- Dehydro Nisoldipine-d7 (CAS 1329836-20-5)
- Dehydro Felodipine-d3 (CAS 1189916-52-6)
- 14-dehydro zymostenol (CAS 19431-20-0)
- Dehydro diosgenin (CAS 1672-65-7)
- Dehydro-eletriptanDISCONTINUED, offer B120728 or B120725 (CAS 188113-72-6)
- 6,7-Dehydro Prednisolone 21-Acetate (CAS 2427-45-4)
Recommended Standards
- 2,2-Dimethyl-1-(triphenylphosphoranylidene)propyl acetate (CAS 518300-02-2)
- 3,4-Bis(4-methoxyphenyl)-1-(thiophene-2-carbonyl)-1H-pyrazole (CAS 955964-56-4)
- 2-(2,3-Dihydrobenzofuran-5-yl)-N-(4-(furan-2-yl)-6-methylbenzo[d]thiazol-2-yl)acetamide (CAS 2288709-60-2)
- 4-((4-(N-mesitylsulfamoyl)phenyl)amino)-4-oxobutanoic acid (CAS 457922-04-2)
- Ethyl 3-cyano-2-oxo-6-phenyl-1,2-dihydropyridine-4-carboxylate (CAS 18060-61-2)
- 7-bromo-3-ethyl-1H-1,6-naphthyridin-2-one (CAS 2589531-29-1)
- 2-(2-Phenylphenoxy)acetohydrazide (CAS 379255-60-4)
- 1-(2-(Dimethylamino)ethyl)-3-ethylurea (CAS 62594-29-0)
- 1-(3,5-Dimethylphenyl)cyclopropan-1-amine (CAS 1154178-50-3)
- Hydroxyacetic Acid Hydrazide (CAS 3530-14-1)
- Domperidone-D6 (CAS 1329614-18-7)
- 2,4-Di-tert-Butyl-6-[(1E)-(hydroxyimino)methyl]phenol (CAS 118371-00-9)
- 1-(2-Bromo-1-(cyclopropylmethoxy)ethyl)-2-fluorobenzene (CAS 1250823-53-0)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
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