2-(4-(1-(2-(Dimethylamino)ethyl)-4-hydroxy-5-oxo-3-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-2-yl)phenoxy)acetamide CAS 617694-16-3
| CAS No. | 617694-16-3 |
| Molecular Formula | C21H23N3O5S |
| Molecular Weight | 429.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-(1-(2-(Dimethylamino)ethyl)-4-hydroxy-5-oxo-3-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-2-yl)phenoxy)acetamide.
2-(4-(1-(2-(Dimethylamino)ethyl)-4-hydroxy-5-oxo-3-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-2-yl)phenoxy)acetamide (CAS 617694-16-3), molecular formula C21H23N3O5S and molecular weight 429.49 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-(1-(2-(Dimethylamino)ethyl)-4-hydroxy-5-oxo-3-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-2-yl)phenoxy)acetamide (C21H23N3O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H23N3O5S |
| Molecular Weight | 429.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dimethylamino Standards
- 4-((1-(dimethylamino)-3-(4-(3-methoxyphenethyl)phenoxy)propan-2-yl)oxy)-4-oxobutanoic acid (CAS CATO-C4X-291341)
- 3',6'-Bis(dimethylamino)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-5-carboxylic acid (CAS 150322-05-7)
- 3',6'-Bis(dimethylamino)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid (CAS 150322-06-8)
- 1-((2-(Dimethylamino)ethyl)amino)-5,8-dihydroxy-4-((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione (CAS 134566-65-7)
- 5-(4-(Dimethylamino)benzylidene)-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione (CAS 86872-80-2)
- 5-Benzyl-3-(4-(dimethylamino)phenyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione (CAS 308101-48-6)
- (E)-4-((1-(dimethylamino)-3-(2-(3-methoxyphenethyl)phenoxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid (CAS CATO-C4X-291342)
- 1-(2-(Dimethylamino)ethyl)-4-(3-fluoro-4-methylbenzoyl)-3-hydroxy-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 618075-75-5)
Recommended Standards
- 1-(2-Fluorophenyl)-4-(1-(3-phenoxypropyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one (CAS 847396-12-7)
- 2-(Fmoc-amino)-2-(1,1-dioxo-4-tetrahydrothiopyranyl)acetic Acid (CAS 369402-98-2)
- (4AS,8S,8aS)-2-acetamido-6-methyl-4-oxo-8a-(2-(phenylthio)acetyl)-1,4,4a,5,8,8a-hexahydroquinazolin-8-yl acetate (CAS 86971-03-1)
- 2-{[(4-methoxyphenyl)methyl]sulfanyl}-5-[1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]-1,3,4-oxadiazole (CAS 477709-80-1)
- 3-(4-Ethoxycarbonylphenyl)isonicotinic acid (CAS 1261929-79-6)
- N-(9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)acetamide (CAS 1443367-96-1)
- (4-Amino-2-methylphenyl)(morpholino)methanone (CAS 869859-95-0)
- Ethyl 2-(4-chlorophenyl)-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 175201-54-4)
- 7-Chloro-4-((4-chlorophenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]thiazine (CAS 338777-92-7)
- (3-Fluorotetrahydro-2H-pyran-3-yl)methanamine (CAS 1557978-39-8)
- 2-Fluoro-4-propoxyphenylboronic acid (CAS 1107603-51-9)
- 2-(2-(Pyridin-2-yl)ethyl)aniline (CAS 50385-28-9)
- 2-(4-(Benzyloxy)-3-(trifluoromethyl)phenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane (CAS 2096995-52-5)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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