1-(2-(Dimethylamino)ethyl)-4-(3-fluoro-4-methylbenzoyl)-3-hydroxy-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one CAS 618075-75-5
| CAS No. | 618075-75-5 |
| Molecular Formula | C22H22FN3O5 |
| Molecular Weight | 427.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 427.43 g/mol gives 1-(2-(Dimethylamino)ethyl)-4-(3-fluoro-4-methylbenzoyl)-3-hydroxy-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(2-(Dimethylamino)ethyl)-4-(3-fluoro-4-methylbenzoyl)-3-hydroxy-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 618075-75-5), molecular formula C22H22FN3O5 and molecular weight 427.43 g/mol, is a CATO reference standard with documented purity and traceability.
1-(2-(Dimethylamino)ethyl)-4-(3-fluoro-4-methylbenzoyl)-3-hydroxy-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one (C22H22FN3O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H22FN3O5 |
| Molecular Weight | 427.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Dimethylamino Standards
- 1-(2-(Dimethylamino)ethyl)-4-(3-fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 618074-10-5)
- (E)-4-((1-(dimethylamino)-3-(2-(3-methoxyphenethyl)phenoxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid (CAS CATO-C4X-291342)
- 5-Benzyl-3-(4-(dimethylamino)phenyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione (CAS 308101-48-6)
- 5-(4-(Dimethylamino)benzylidene)-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione (CAS 86872-80-2)
- (Z)-3-((3-((Dimethylamino)methyl)phenylamino)(phenyl)methylene)-N-methyl-2-oxoindoline-6-carboxamide (CAS 334951-92-7)
- 1-((2-(Dimethylamino)ethyl)amino)-5,8-dihydroxy-4-((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione (CAS 134566-65-7)
- 2-(4-(1-(2-(Dimethylamino)ethyl)-4-hydroxy-5-oxo-3-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-2-yl)phenoxy)acetamide (CAS 617694-16-3)
- 4-((1-(dimethylamino)-3-(4-(3-methoxyphenethyl)phenoxy)propan-2-yl)oxy)-4-oxobutanoic acid (CAS CATO-C4X-291341)
Recommended Standards
- N-[(4-Fluorophenyl)methyl]-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775554-63-6)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(2-fluorophenyl)acetamide (CAS 1775554-40-9)
- N-(4-(Diphenylphosphoryl)phenyl)-4-methoxybenzamide (CAS 90304-96-4)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-[(4-fluorophenyl)methyl]acetamide (CAS 1775533-43-1)
- 2-Chlorobenzyl carbamimidothioate hydrochloride (CAS 3778-85-6)
- Vortioxetine Impurity 3 (CAS 508234-03-5)
- Ethyl 3-amino-1-methylcyclobutane-1-carboxylate (CAS 1822972-08-6)
- N-Ethylhydroxylamine (CAS 624-81-7)
- 4-(2,4-Dibromophenyl)morpholine (CAS 1208077-57-9)
- 1-Methyl-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine (CAS 794451-98-2)
- (6-Fluoro-2,3-dihydrobenzofuran-7-yl)methanamine (CAS 1891255-32-5)
- 2,2,2-Trifluoro-1-(4-fluoro-3,5-dimethylphenyl)ethanone (CAS 1256467-41-0)
- Ethyl 3-[4-(2,4-dichlorobenzoyl)-1-methyl-1H-pyrrol-2-yl]acrylate (CAS 400077-69-2)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
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