3-Chlorobenzoyl Chloride CAS 618-46-2
| CAS No. | 618-46-2 |
| Molecular Formula | C7H4Cl2O |
| Molecular Weight | 175.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chlorobenzoyl Chloride is closely related to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Chlorobenzoyl Chloride (CAS 618-46-2), molecular formula C7H4Cl2O and molecular weight 175.01 g/mol, is a CATO reference standard with documented purity and traceability.
3-Chlorobenzoyl Chloride (C7H4Cl2O) contains a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4Cl2O |
| Molecular Weight | 175.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Chlorobenzoyl Standards
- 2-Chlorobenzoyl Chloride (CAS 609-65-4)
- O-(4-Chlorobenzoyl)hydroxylamine (CAS 872851-33-7)
- 4-Chlorobenzoyl-d4 Chloride (CAS 87367-51-9)
- (2-Chlorobenzoyl)hydrazine (CAS 5814-05-1)
- 2-(3-Chlorobenzoyl)acetonitrile (CAS 21667-62-9)
- 3-Chlorobenzoyl isocyanate (CAS 74703-17-6)
- 4-Chlorobenzoyl isocyanate (CAS 4461-36-3)
- 4-Chlorobenzoyl chloride-α-<SUP>13</SUP>C (CAS 138534-67-5)
Recommended Standards
- 2,5-Dichlorobenzaldehyde (CAS 6361-23-5)
- Ixazomib Impurity 13 (CAS 6334-18-5)
- 2,6-dichlorobenzaldehyde (CAS 83-38-5)
- Ixazomib Impurity 14 (CAS 6287-38-3)
- 2-(3-Piperidinyl)-4-thiazolecarbonitrile (CAS 2091782-47-5)
- Sulfachlorpyridazine-d4 (CAS 1795037-54-5)
- (5-(Methylsulfonamido)pyridin-3-yl)boronic acid (CAS 1382475-73-1)
- (E)-N'-(1-(3-aminophenyl)ethylidene)-2-((1-bromonaphthalen-2-yl)oxy)acetohydrazide (CAS 349468-16-2)
- (S,E)-4-(methylsulfonyl)-1-phenylbut-3-en-2-amine hydrochloride (CAS 170112-17-1)
- Methyl 2-(trans-4-(aminomethyl)cyclohexyl)acetate hydrochloride (CAS 2245840-94-0)
- 1-Cyclohexyl-5-oxo-N-(4-phenoxyphenyl)pyrrolidine-3-carboxamide (CAS 669696-41-7)
- 2-amino-3-bromo-1,7-naphthyridine-6-carboxylic acid (CAS 2691878-65-4)
- Lead(II) hexafluorosilicate dihydrate (CAS 1310-03-8)
- Gastric Inhibitory Polypeptide (human) (CAS 100040-31-1)
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