ethyl 5-amino-1-(2-fluorophenyl)pyrazole-4-carboxylate CAS 618070-65-8

Purity 97%+In StockPharmaceutical Standards
CAS No.618070-65-8
Molecular FormulaC12H12FN3O2
Molecular Weight249.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

ethyl 5-amino-1-(2-fluorophenyl)pyrazole-4-carboxylate CAS 618070-65-8 chemical structure

Description

CATO supplies ethyl 5-amino-1-(2-fluorophenyl)pyrazole-4-carboxylate (CAS 618070-65-8), a certified reference material (molecular formula C12H12FN3O2, MW 249.24 g/mol) for analytical method development and quality control.

The molecular framework of ethyl 5-amino-1-(2-fluorophenyl)pyrazole-4-carboxylate (C12H12FN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H12FN3O2
Molecular Weight249.24 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF-containing
Nitrogen Atoms3

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