4-(3-Fluoro-4-methylbenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one CAS 618073-86-2
| CAS No. | 618073-86-2 |
| Molecular Formula | C24H18F2N2O3 |
| Molecular Weight | 420.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(3-Fluoro-4-methylbenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-(3-Fluoro-4-methylbenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618073-86-2), a certified reference material (molecular formula C24H18F2N2O3, MW 420.41 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(3-Fluoro-4-methylbenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 420.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(3-Fluoro-4-methylbenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H18F2N2O3 |
| Molecular Weight | 420.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- (R)-2-(6-Fluoro-1H-benzo[d]imidazol-1-yl)-9-(8-fluorochroman-4-yl)-7H-purin-8(9H)-one (CAS 911824-55-0)
- 2-Fluoro-N-(5-((2-((4-fluorobenzyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide (CAS 896022-88-1)
- 9-Fluoro-11β-hydroxy-17,20:20,21-bis(methylenedioxy)-pregna-1,4-dien-3-one (CAS 3800-34-8)
- 5-Fluoro-N-(3-(morpholinosulfonyl)phenyl)benzo[b]thiophene-2-carboxamide (CAS 868268-81-9)
- 2-Fluoro-4,4'-bis((1s,4r)-4-propylcyclohexyl)-1,1'-biphenyl (CAS 102714-93-2)
- 2-Fluoro-N-(5-fluoro-2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-4-(2-hydroxypropan-2-yl)benzamide (CAS 1418128-72-9)
- [fluoro(iodo)methyl]-triphenyl-phosphonium (CAS 777796-43-7)
- 4-Fluoro-N'-[1-(4-methylbenzenesulfonyl)piperidine-4-carbonyl]benzohydrazide (CAS 478030-16-9)
Recommended Standards
- 2-Hydroxy-4-((3-(N-hydroxyacetamido)propyl)amino)-2-(2-((3-(N-hydroxyacetamido)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid (CAS 35418-52-1)
- 7-O-Methyl morroniside (CAS 41679-97-4)
- 2-(3-(Benzyloxy)-4-methoxyphenyl)-5,7-dihydroxy-3-methoxy-4H-chromen-4-one (CAS 62507-01-1)
- Ethyl 1-((1,3-dioxoisoindolin-2-yl)methyl)-6,7-dimethoxyisoquinoline-4-carboxylate (CAS 264188-67-2)
- 4,5,6,7-Tetrahydro-1H-pyrazolo[3,4-c]pyridine (CAS 871792-61-9)
- Chloropyramine (CAS 59-32-5)
- 2-(2,3-Dihydro-1h-1,3-benzodiazol-2-ylidene)-3-oxobutanenitrile (CAS 301344-08-1)
- Sulindac Sulfide Methyl Ester (CAS 106647-49-8)
- 1-(4-(Azetidine-3-carbonyl)piperazin-1-yl)ethan-1-one hydrochloride (CAS 1829892-64-9)
- (2-Chloro-5,7-dimethylquinolin-3-yl)methanol (CAS 1017464-08-2)
- Lamotrigine EP Impurity E (CAS 50-45-3)
- 3-Bromo-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 95607-07-1)
- 1,3,3-Trimethylpiperazin-2-one (CAS 890926-94-0)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com