1-(2-(Diethylamino)ethyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-5-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one CAS 618074-77-4
| CAS No. | 618074-77-4 |
| Molecular Formula | C25H29FN2O5 |
| Molecular Weight | 456.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(2-(Diethylamino)ethyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-5-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one (C25H29FN2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 1-(2-(Diethylamino)ethyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-5-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one (CAS 618074-77-4), a certified reference material (molecular formula C25H29FN2O5, MW 456.51 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H29FN2O5 |
| Molecular Weight | 456.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Diethylamino Standards
- 1-(2-(Diethylamino)ethyl)-4-(3-fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 618074-09-2)
- 1-(2-(Diethylamino)ethyl)-5-(4-ethylphenyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-1H-pyrrol-2(5H)-one (CAS 618074-93-4)
- 1-(2-(Diethylamino)ethyl)-4-(3,4-dimethoxybenzoyl)-3-hydroxy-5-(4-hydroxyphenyl)-1H-pyrrol-2(5H)-one (CAS 618080-95-8)
- 7,7-Bis(4-(diethylamino)-2-methylphenyl)furo[3,4-b]pyrazin-5(7H)-one (CAS 50668-35-4)
- Methyl 2-(2-(3-(diethylamino)-1-oxo-1H-benzo[f]chromen-2-yl)ethyl)-6-methoxybenzoate (CAS 365542-83-2)
- N-(5-(diethylamino)pentan-2-yl)-2-(2-(5-nitrofuran-2-yl)vinyl)quinoline-4-carboxamide (CAS 70762-66-2)
- 6'-(Diethylamino)-2'-(phenylamino)-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one (CAS 29512-46-7)
- 1-(2-(Diethylamino)ethyl)-3-hydroxy-4-(4-isopropoxy-3-methylbenzoyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one (CAS 371125-84-7)
Recommended Standards
- 5,5',5''-(Benzene-1,3,5-triyl)tris(thiophene-2-carboxylic acid) (CAS 1442006-75-8)
- 1-(4-((2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)sulfonyl)piperazin-1-yl)-2-(6-methylbenzofuran-3-yl)ethan-1-one (CAS 847939-23-5)
- 2,5-Dioxopyrrolidin-1-yl 3-(2-(5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)propanoate (CAS 1260092-31-6)
- 2,2'-(((Sulfonylbis(4,1-phenylene))bis(azanylylidene))bis(methanylylidene))diphenol (CAS 7251-84-5)
- 2-AMINO-2-(4-(METHYLSULFONYL)PHENYL)ETHAN-1-OL HCL (CAS 1270556-34-7)
- Propyl 2-amino-4-(4-methoxyphenyl)-5-methylthiophene-3-carboxylate (CAS 905011-75-8)
- Methyl 4-[3-(tert-Butoxy)-3-oxopropyl]-1H-pyrrole-2-carboxylate (CAS 1041430-89-0)
- Ethyl 2-(N-phenylformamido)acetate (CAS 54915-69-4)
- 6-Methoxy-5-methylpicolinohydrazide (CAS 1378381-41-9)
- Clodronate Disodium EP Impurity A Pyridinium Salt (CAS 134757-52-1 (free acid))
- Ethyl 2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)cyclopropanecarboxylate (CAS 669087-47-2)
- Methyl 2-imino-5-(4-methoxybenzoyl)-2,3-dihydrothiazole-4-carboxylate (CAS 941868-48-0)
- 6-Amino-1-butyl-5-propylamino-1H-pyrimidine-2,4-dione (CAS 571149-81-0)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
Why CATO?
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