4-(3-Fluoro-4-methylbenzoyl)-1-(furan-2-ylmethyl)-3-hydroxy-5-(4-hydroxyphenyl)-1H-pyrrol-2(5H)-one CAS 618075-79-9
| CAS No. | 618075-79-9 |
| Molecular Formula | C23H18FNO5 |
| Molecular Weight | 407.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(3-Fluoro-4-methylbenzoyl)-1-(furan-2-ylmethyl)-3-hydroxy-5-(4-hydroxyphenyl)-1H-pyrrol-2(5H)-one (CAS 618075-79-9) is a high-purity analytical reference standard with the molecular formula C23H18FNO5 and a molecular weight of 407.39 g/mol.
The molecular framework of 4-(3-Fluoro-4-methylbenzoyl)-1-(furan-2-ylmethyl)-3-hydroxy-5-(4-hydroxyphenyl)-1H-pyrrol-2(5H)-one (C23H18FNO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(3-Fluoro-4-methylbenzoyl)-1-(furan-2-ylmethyl)-3-hydroxy-5-(4-hydroxyphenyl)-1H-pyrrol-2(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H18FNO5 |
| Molecular Weight | 407.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-fluoro-5-methoxybenzoic acid (CAS 2243516-10-9)
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- 3-Phenyl-N'-[(1E)-[2-(trifluoromethyl)phenyl]methylidene]-1H-indole-2-carbohydrazide (CAS 338415-07-9)
- Ethyl 2-({5-[3-(trifluoromethoxy)benzamido]-1,3,4-thiadiazol-2-yl}sulfanyl)acetate (CAS 329699-49-2)
- 3-(4-(2-(3-Chlorophenyl)-2-oxoethyl)phenyl)-5-(methoxymethyl)oxazolidin-2-one (CAS 79039-02-4)
- 6-Chloro-2-(4-ethoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-33-1)
- 3-[(cyanomethyl)sulfanyl]-1-phenyl-5,6,7,8-tetrahydro-4-isoquinolinecarbonitrile (CAS 315246-86-7)
- Phthalic acid, bis-8-methylnonyl ester (CAS 89-16-7)
- N-[(3-Fluorophenyl)methyl]-2-methoxyaniline (CAS 1019565-39-9)
- 1,5-Anthracenedicarbonitrile (CAS 200353-90-8)
- (1R,2R)-2-Hydroxy-1,2-diphenylethyl 2-(diphenylphosphino)benzoate (CAS 1220999-75-6)
- 3-benzylpiperazin-2-one hydrochloride (CAS 1214697-44-5)
- 3-Methyl-2-(trifluoromethyl)pyridine (CAS 1620-78-6)
- Liraglutide(5-31)TFA Salt (CAS CATO-C4X-19924)
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