(5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazol-4-yl)(2-chlorophenyl)methanone CAS 618092-08-3

Purity 97%+In StockPharmaceutical Standards
CAS No.618092-08-3
Molecular FormulaC16H10Cl2FN3O
Molecular Weight350.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazol-4-yl)(2-chlorophenyl)methanone CAS 618092-08-3 chemical structure

Description

The molecular framework of (5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazol-4-yl)(2-chlorophenyl)methanone (C16H10Cl2FN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

(5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazol-4-yl)(2-chlorophenyl)methanone (CAS 618092-08-3) is a high-purity analytical reference standard with the molecular formula C16H10Cl2FN3O and a molecular weight of 350.17 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazol-4-yl)(2-chlorophenyl)methanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H10Cl2FN3O
Molecular Weight350.17 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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