2-Amino-6-(trifluoromethyl)-3-[(E)-{[2-(trifluoromethyl)phenyl]methylidene}amino]-3,4-dihydropyrimidin-4-one CAS 866145-78-0
| CAS No. | 866145-78-0 |
| Molecular Formula | C13H8F6N4O |
| Molecular Weight | 350.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Amino-6-(trifluoromethyl)-3-[(E)-{[2-(trifluoromethyl)phenyl]methylidene}amino]-3,4-dihydropyrimidin-4-one (CAS 866145-78-0) is a high-purity analytical reference standard with the molecular formula C13H8F6N4O and a molecular weight of 350.22 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-Amino-6-(trifluoromethyl)-3-[(E)-{[2-(trifluoromethyl)phenyl]methylidene}amino]-3,4-dihydropyrimidin-4-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 350.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Amino-6-(trifluoromethyl)-3-[(E)-{[2-(trifluoromethyl)phenyl]methylidene}amino]-3,4-dihydropyrimidin-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H8F6N4O |
| Molecular Weight | 350.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 2-Amino-6-(3-bromophenyl)-4-phenylpyridine-3-carbonitrile (CAS 361198-37-0)
- 3-Amino-2-(4-(benzyloxy)-3-bromophenyl)propanoic acid (CAS 299438-98-5)
- (4-(2-Amino-4-chlorophenyl)piperazin-1-yl)(4-chlorophenyl)methanone (CAS 887833-53-6)
- (4-(4-Amino-2-chlorophenyl)piperazin-1-yl)(4-chlorophenyl)methanone (CAS 640759-18-8)
- 1-(2-Amino-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-1-(2,4-dichlorophenyl)butan-2-one (CAS 866039-10-3)
- (5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazol-4-yl)(2-chlorophenyl)methanone (CAS 618092-08-3)
- Ethyl 3-amino-6-phenyl-4-(trifluoromethyl)furo[2,3-b]pyridine-2-carboxylate (CAS 160436-48-6)
- 2-Amino-5-oxo-4-(4-(trifluoromethoxy)phenyl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 664974-38-3)
Recommended Standards
- 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-((phosphonooxy)methyl)tetrahydrofuran-2-yl)-4-imino-1,4-dihydropyridine-3-carboxylic acid (CAS 65411-71-4)
- 4-(4-(2,4-Dichlorophenyl)thiazol-2-yl)benzoic acid (CAS 320420-89-1)
- (5'-Phenyl-[1,1':3',1''-terphenyl]-4-yl)boronic acid (CAS 491612-72-7)
- 4-(4-(3,4-Dichlorophenyl)thiazol-2-yl)benzoic acid (CAS 338407-84-4)
- 4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde (CAS 1111237-78-5)
- Neopentyl 2-chloro-2-oxoacetate (CAS 209848-82-8)
- 1-bromo-2-(bromomethyl)-3-(trifluoromethyl)benzene (CAS 69902-84-7)
- 2701AF 3-[4-(Trifluoromethyl)phenoxy]piperidine 902836-91-3 C12H14F3NO (CAS 902836-91-3)
- 1-(Pyridin-3-yl)butane-1,3-dione (CAS 3594-37-4)
- Phytomenadione/Vitamin K1 Impurity 130 (CAS CATO-C4X-2207130)
- 4-Chloro-N-(3-iodophenyl)benzamide (CAS 897761-86-3)
- Isopropyl 2,4-dioxohexahydropyrimidine-5-carboxylate (CAS 92264-76-1)
- 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate (sodium salt) 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphate (sodium salt) 18:0-22:6 PA 474943-30-1 PA(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) (CAS 474943-30-1)
- D-[His]1-Semaglutide (CAS CATO-C4X-222652)
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