3-(2-Chlorophenyl)-1-(o-tolyl)-1H-pyrazol-5-amine CAS 618098-40-1
| CAS No. | 618098-40-1 |
| Molecular Formula | C16H14ClN3 |
| Molecular Weight | 283.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(2-Chlorophenyl)-1-(o-tolyl)-1H-pyrazol-5-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-(2-Chlorophenyl)-1-(o-tolyl)-1H-pyrazol-5-amine (CAS 618098-40-1), molecular formula C16H14ClN3 and molecular weight 283.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(2-Chlorophenyl)-1-(o-tolyl)-1H-pyrazol-5-amine (C16H14ClN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H14ClN3 |
| Molecular Weight | 283.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 1-benzyl-3-(3-chlorophenyl)-1H-pyrazol-5-amine (CAS 1154569-19-3)
- 1-(4-Chlorophenyl)-4-p-tolyl-1H-pyrazol-5-amine (CAS 1202029-96-6)
- 1-(3-Chlorophenyl)-3-(m-tolyl)-1H-pyrazol-5-amine (CAS 618098-32-1)
- 1-(3-Chlorophenyl)-3-(o-tolyl)-1H-pyrazol-5-amine (CAS 618098-33-2)
- 1-(3-Chlorophenyl)-3-(p-tolyl)-1H-pyrazol-5-amine (CAS 618098-27-4)
- 1-(3-Chlorophenyl)-4-(2-methylphenyl)-1H-pyrazol-5-amine (CAS 324009-02-1)
- 1-(3-Chlorophenyl)-4-(m-tolyl)-1H-pyrazol-5-amine (CAS 242797-15-5)
- 1-(3-Chlorophenyl)-4-(p-tolyl)-1H-pyrazol-5-amine (CAS 242797-19-9)
Recommended Standards
- 2-Chloro-N-methyl-N-(p-tolyl)quinazolin-4-amine (CAS 827030-34-2)
- 3-(2-Chlorophenyl)-1-(p-tolyl)-1H-pyrazol-5-amine (CAS 618092-92-5)
- 2-Chloro-N-(4-methylbenzyl)quinazolin-4-amine (CAS 938524-71-1)
- 3-(4-Chlorophenyl)-1-(o-tolyl)-1H-pyrazol-5-amine (CAS 618098-35-4)
- 4-Chloro-2,3-difluorobenzonitrile (CAS 1224881-80-4)
- N-methyl-1-(2-(piperidin-4-yl)phenyl)methanamine dihydrochloride (CAS 1853217-73-8)
- Bambuterol-d9 Hydrochloride (CAS 1794810-59-5)
- 1-(6-fluoro-2-naphthyl)ethanone (CAS 33627-02-0)
- (2,6-Dichloro-4-fluorophenyl)hydrazine (CAS 119453-09-7)
- 2-(Difluoromethyl)-6-hydroxy-4-(trifluoromethoxy)pyridine-3-acetic acid (CAS 1806047-98-2)
- Cefuroxime-d3 (CAS 1803240-98-3)
- 3-Bromo-6-chloro-2H-chromen-2-one (CAS 1220702-34-0)
- 2-Chloro-6-(dimethylamino)benzaldehyde (CAS 1021240-67-4)
- β-Bag Cell Peptide (Aplysia californica) (CAS 109024-47-7)
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