3-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid CAS 618102-39-9
| CAS No. | 618102-39-9 |
| Molecular Formula | C16H10ClFN2O2 |
| Molecular Weight | 316.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid.
CATO supplies 3-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-39-9), a certified reference material (molecular formula C16H10ClFN2O2, MW 316.71 g/mol) for analytical method development and quality control.
The molecular framework of 3-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (C16H10ClFN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10ClFN2O2 |
| Molecular Weight | 316.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- (2Z)-3-(4-Chlorophenyl)-2-cyano-N-(4-fluorophenyl)-3-hydroxyprop-2-enamide (CAS 866151-39-5)
- 1-(2-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-81-1)
- 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618383-16-7)
- 1-(4-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-74-2)
- 3-(4-Chlorophenyl)-1-((4-fluorophenyl)amino)-1H-pyrrole-2,5-dione (CAS 271254-37-6)
- 3-(4-Chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-55-9)
- 5-(2-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid (CAS 477712-06-4)
- 5-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid (CAS 477712-02-0)
Recommended Standards
- 3-(6-Chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)acrylic acid (CAS 727977-30-2)
- 4-Chloro-6-fluoro-2-(4-hydroxyphenyl)quinoline-8-carboxamide (CAS 655222-76-7)
- 5-(3-Chlorothiophen-2-yl)-1-trifluoromethanesulfonyl-1H-pyrazole (CAS 318951-83-6)
- 6-Chloro-4-(3-methylbut-1-yn-1-yl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one (CAS 214287-63-5)
- Methyl 5-bromo-2-methoxypyrimidine-4-carboxylate (CAS 1398504-36-3)
- Benzyl (5-azaspiro[2.3]Hexan-1-yl)carbamate (CAS 1936154-42-5)
- Tert-butyl (1-(1-(hydroxymethyl)cyclobutyl)ethyl)carbamate (CAS 2384565-33-5)
- 2,2,2-Trifluoro-N'-(pyrazin-2-yl)acetohydrazide (CAS 837430-15-6)
- 4-(3-Fluorophenoxy)-2,2-dimethylbutanoic acid (CAS 1226040-09-0)
- 2-((2,4-Dichlorobenzyl)thio)-4,5-dimethoxypyrimidine (CAS 339275-88-6)
- Cefixime EP Impurity A (CAS 1614255-90-1)
- 2-Amino-4-benzyl-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile (CAS 489397-49-1)
- 3-Acetylbenzo[d]oxazol-2(3H)-one (CAS 24963-28-8)
- Semaglutide Impurity 123 (CAS 71997-93-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com