3-(4-Chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazole-5-carboxylic acid CAS 618102-55-9
| CAS No. | 618102-55-9 |
| Molecular Formula | C16H10ClFN2O2 |
| Molecular Weight | 316.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(4-Chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazole-5-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(4-Chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-55-9) is a high-purity analytical reference standard with the molecular formula C16H10ClFN2O2 and a molecular weight of 316.71 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 3-(4-Chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazole-5-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 316.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(4-Chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10ClFN2O2 |
| Molecular Weight | 316.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- (2Z)-3-(4-Chlorophenyl)-2-cyano-N-(4-fluorophenyl)-3-hydroxyprop-2-enamide (CAS 866151-39-5)
- 1-(2-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-81-1)
- 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618383-16-7)
- 1-(4-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-74-2)
- 3-(4-Chlorophenyl)-1-((4-fluorophenyl)amino)-1H-pyrrole-2,5-dione (CAS 271254-37-6)
- 3-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-39-9)
- 5-(2-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid (CAS 477712-06-4)
- 5-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid (CAS 477712-02-0)
Recommended Standards
- 3-(6-Chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)acrylic acid (CAS 727977-30-2)
- 4-Chloro-6-fluoro-2-(4-hydroxyphenyl)quinoline-8-carboxamide (CAS 655222-76-7)
- 5-(3-Chlorothiophen-2-yl)-1-trifluoromethanesulfonyl-1H-pyrazole (CAS 318951-83-6)
- 4-(5-Chloro-6-dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenol (CAS 1311279-12-5)
- 2-Chloro-3-iodo-5-nitropyridine (CAS 25391-60-0)
- 3-(2,4-Dichlorophenyl)-8-methyl-1,4-diazaspiro[4.5]Dec-3-ene-2-thione (CAS 899912-53-9)
- N1-Nitroso Lurbinectedin (CAS CATO-C4X-31141)
- 1-(1,3-Dimethyl-1h-1,2,4-triazol-5-yl)-4-methylcyclohexan-1-amine (CAS 1249998-13-7)
- (R)-2-(1-methylpyrrolidin-2-yl)acetic acid hydrochloride (CAS 1174655-95-8)
- 103488-38-6 2,5-di-O-galloyl-4,6-O-(S)-hexahydroxy-diphenoyl-D-gluconic acid Punigluconin (CAS 103488-38-6)
- 3,6-Bis(trifluoromethyl)benzene-1,2-diamine (CAS 106877-22-9)
- 4-Bromo-2-(Difluoromethyl)benzyl bromide (CAS 1261448-03-6)
- N,N-Diethyl-2-(thiophen-2-yl)quinolin-4-amine hydrobromide (CAS 853349-75-4)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
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