1-(3-Chlorophenyl)-3-(thiophen-2-yl)-1H-pyrazole-5-carboxylic acid CAS 618382-83-5
| CAS No. | 618382-83-5 |
| Molecular Formula | C14H9ClN2O2S |
| Molecular Weight | 304.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(3-Chlorophenyl)-3-(thiophen-2-yl)-1H-pyrazole-5-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(3-Chlorophenyl)-3-(thiophen-2-yl)-1H-pyrazole-5-carboxylic acid (CAS 618382-83-5), molecular formula C14H9ClN2O2S and molecular weight 304.75 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 1-(3-Chlorophenyl)-3-(thiophen-2-yl)-1H-pyrazole-5-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 304.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(3-Chlorophenyl)-3-(thiophen-2-yl)-1H-pyrazole-5-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9ClN2O2S |
| Molecular Weight | 304.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 5-(4-Chlorophenyl)-2-(1H-pyrrol-1-yl)-1,3-thiazole-4-carboxylic acid (CAS 1623080-69-2)
- 1-(2-Chlorophenyl)-3-(thiophen-2-yl)-1H-pyrazole-5-carboxylic acid (CAS 618382-88-0)
- 1-(4-Chlorophenyl)-3-(thiophen-2-yl)-1H-pyrazole-5-carboxylic acid (CAS 618382-79-9)
- 2-((6-(4-Chlorophenyl)-3-cyanopyridin-2-yl)thio)acetic acid (CAS 326915-38-2)
- 3-(4-Chlorophenyl)-3-(4-ethoxyphenyl)propanoic acid (CAS 1225976-34-0)
- Ethyl 7-(4-chlorophenyl)-4,7-dihydro[1,2,4]-triazolo[1,5-a]pyrimidine-6-carboxylate (CAS 1306738-76-0)
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Recommended Standards
- 1-(4-Chloro-3-nitrobenzenesulfonyl)piperidine (CAS 53162-43-9)
- 1-((2-Chloro-5-nitrophenyl)sulfonyl)piperidine (CAS 53162-05-3)
- 1-[(2-chloropyridin-3-yl)sulfonyl]piperidine-4-carboxylic acid (CAS 929975-76-8)
- Ethyl 6-(chlorosulfonyl)chromane-3-carboxylate (CAS 1495410-93-9)
- tert-Butyl (R)-(1,2,3,4-tetrahydroquinolin-3-yl)carbamate (CAS 1187928-12-6)
- 2-(3-Aminopropyl)-6-(pyridin-4-yl)pyridazin-3(2H)-one (CAS 1283109-45-4)
- 2-Chloromethyl-4,6-dimethoxy-3-methylbenzaldehyde, 97% (CAS 166322-69-6)
- (S)-Stiripentol (CAS 144017-66-3)
- Ethyl 4-isopropylisoxazole-3-carboxylate (CAS 1332635-53-6)
- 1,1'-Bi[2-naphthoic acid] (CAS 99827-46-0)
- 5-((O-tolyloxy)methyl)-1,3,4-oxadiazol-2-amine (CAS 21520-91-2)
- 2,5-Dichloropyridine-4-boronic acid (CAS 847664-64-6)
- 3-(Methylsulfanyl)-4h-1,2,4-triazol-4-amine (CAS 65901-91-9)
- Acetyl Hexapeptide-38 (CAS 1400634-44-7)
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