Adrenaline EP Impurity C HCl CAS 62-13-5
| CAS No. | 62-13-5 |
| Molecular Formula | C9H11NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 217.65 g/mol gives Adrenaline EP Impurity C HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Adrenaline EP Impurity C HCl (CAS 62-13-5, C9H11NO3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Adrenaline EP Impurity C HCl (C9H11NO3HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H11NO3 HCl |
| Molecular Weight | 217.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Adrenaline Standards
- Adrenaline Impurity 34 (CAS 1095714-91-2)
- rac-Adrenaline EP Impurity D TFA salt (CAS 1095714-91-2(Free Base))
- Adrenaline Impurity 88 (CAS 139183-81-6)
- Adrenaline Impurity 42 (CAS 18191-22-5)
- Adrenaline Impurity 23 (CAS 1894824-44-2)
- Adrenaline Impurity 16 (CAS 2234-25-5)
- Rac-Adrenaline EP Impurity F (Epinephrine Sulfonic Acid) (CAS 26405-77-6)
- Adrenaline Impurity 17 HCl (CAS 29705-82-6)
Recommended Standards
- Dexamethasone impurity 91 (CAS CATO-C4X-116591)
- Tafluprost Impurity 16 (CAS 209861-01-8)
- Losartan EP Impurity L (CAS 230971-71-8)
- 4-Methyl-1-octyn-4-ol (CAS 22128-43-4)
- N-((2-Bromopyridin-4-yl)methyl)-2-chloro-N-cyclopropylacetamide (CAS 1353952-62-1)
- 4-Nitro-1-propoxy-2-(trifluoromethyl)benzene (CAS 1881290-57-8)
- Benzyl 6-(benzyloxy)-1-cyclopropyl-7-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 1391053-23-8)
- 3-chloro-4,5-dimethoxypyridazine (CAS 2096-22-2)
- 1-(3,3-dimethylbutyl)piperazin-2-one hydrochloride (CAS 1423034-59-6)
- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
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