Sofosbuvir Impurity 112 CAS 62062-65-1
| CAS No. | 62062-65-1 |
| Molecular Formula | C6H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sofosbuvir Impurity 112 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Sofosbuvir Impurity 112 (CAS 62062-65-1) is a certified pharmaceutical impurity reference standard with the molecular formula C6H13NO2HCl and a molecular weight of 167.63 g/mol.
The molecular framework of Sofosbuvir Impurity 112 (C6H13NO2HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C6H13NO2 HCl |
| Molecular Weight | 167.63 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 70 (CAS 10065-72-2)
- Sofosbuvir Impurity 109 (CAS 10113-28-7)
- Sofosbuvir Impurity 50 (CAS 1015073-43-4)
- Sofosbuvir Impurity 1 (CAS 1033394-94-3)
- Sofosbuvir O-Desisopropyl O-Ethyl Ester (CAS 1064684-30-5)
- Sofosbuvir Impurity 98 (CAS 111955-47-6)
- Sofosbuvir Impurity 12 (CAS 114262-49-6)
- Sofosbuvir Impurity 2 (CAS 1157884-58-6)
Recommended Standards
- Itraconazole Impurity 16 (CAS CATO-C4X-149716)
- Sofosbuvir Impurity 55 (CAS CATO-C4X-105255)
- Vonoprazan Impurity 176 (CAS 2932441-73-9)
- 5-methyl-N-(propan-2-yl)-1,3,4-thiadiazol-2-amine (CAS 62347-23-3)
- Midazolam Maleate (CAS 59467-94-6)
- 5-(4-Nitrophenyl)-10,15,20-(triphenyl)porphyrin, 98% (CAS 67605-65-6)
- 1-(3-Methylbutyl)-5-nitro-1H-pyrazole (CAS 1864956-08-0)
- Salmeterol EP Impurity F (CAS 1391054-40-2)
- 4-Hydroxy-2-nonenoic acid lactone (CAS 21963-26-8)
- Tumor Targeted Pro-Apoptotic Peptide (CAS 1926163-30-5)
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