2-(2,2,2-Trifluoroethoxy)aniline hydrochloride CAS 62149-83-1
| CAS No. | 62149-83-1 |
| Molecular Formula | C8H8F3NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-(2,2,2-Trifluoroethoxy)aniline hydrochloride is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 227.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-(2,2,2-Trifluoroethoxy)aniline hydrochloride (CAS 62149-83-1), molecular formula C8H8F3NOHCl and molecular weight 227.61 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2,2,2-Trifluoroethoxy)aniline hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8F3NO HCl |
| Molecular Weight | 227.61 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Trifluoroethoxy Standards
- 3-(2,2,2-Trifluoroethoxy)piperidine (CAS 1000931-80-5)
- 6-(2,2,2-Trifluoroethoxy)-N-[2-[[[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl]amino]ethyl]nicotinamide (CAS 1003576-00-8)
- (2-(2,2,2-Trifluoroethoxy)thiazol-5-yl)methanamine (CAS 1003853-96-0)
- 4-(2,2,2-Trifluoroethoxy)piperidine (CAS 1004527-59-6)
- 1-((2,2,2-Trifluoroethoxy)methyl)-1h-pyrazol-4-amine (CAS 1004643-33-7)
- 2-(2,2,2-Trifluoroethoxy)-5-(trifluoromethyl)cyclohexan-1-amine (CAS 1005044-04-1)
- Potassium 2-(2,2,2-trifluoroethoxy)acetate (CAS 1007036-34-1)
- 4-(2,2,2-trifluoroethoxy)butan-1-amine (CAS 1016719-02-0)
Recommended Standards
- 2-amino-2-(1-methylcyclopropyl)propanoic acid hydrochloride (CAS 1798010-75-9)
- Tert-butyl 3-bromo-2-chloro-5,8-dihydro-1,7-naphthyridine-7(6H)-carboxylate (CAS 2306268-82-4)
- (2-Amino-6-chloro-3-(difluoromethyl)pyridin-4-yl)methanol (CAS 1806843-06-0)
- 3-(Ethoxymethyl)pyrrolidine (CAS 946727-50-0)
- 3-[2-(1,3-Dioxolan-2-yl)ethyl]-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one (CAS 866462-51-3)
- 4-Ethynyl-2-(trifluoromethyl)benzonitrile (CAS 239104-49-5)
- 7-(4-Bromophenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 320417-25-2)
- Des-SVEAK impurity (CAS CATO-CPTD789030)
- 1-(Diphenylphosphoryl)-N-(2-(methylthio)-5-(trifluoromethyl)phenyl)methanethioamide (CAS 680213-02-9)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
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