1-((2,2,2-Trifluoroethoxy)methyl)-1h-pyrazol-4-amine CAS 1004643-33-7
| CAS No. | 1004643-33-7 |
| Molecular Formula | C6H8F3N3O |
| Molecular Weight | 195.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-((2,2,2-Trifluoroethoxy)methyl)-1h-pyrazol-4-amine is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-((2,2,2-Trifluoroethoxy)methyl)-1h-pyrazol-4-amine (CAS 1004643-33-7), molecular formula C6H8F3N3O and molecular weight 195.14 g/mol, is a CATO reference standard with documented purity and traceability.
1-((2,2,2-Trifluoroethoxy)methyl)-1h-pyrazol-4-amine (C6H8F3N3O) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-((2,2,2-Trifluoroethoxy)methyl)-1h-pyrazol-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8F3N3O |
| Molecular Weight | 195.14 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoroethoxy Standards
- 5-(2,2,2-Trifluoroethoxy)pyridazin-3(2H)-one (CAS 1346697-88-8)
- 2-(2,2,2-Trifluoroethoxy)pyrimidin-5-ol (CAS 944899-94-9)
- 4-(2,2,2-Trifluoroethoxy)cyclohexan-1-one (CAS 1138244-29-7)
- (2,2,2-Trifluoroethoxy)difluoroacetic Acid (CAS 152538-73-3)
- 2-(2,2,2-Trifluoroethoxy)pyrimidin-5-amine (CAS 1247202-20-5)
- 2-(2,2,2-trifluoroethoxy)pyrimidin-4-amine (CAS 1431654-73-7)
- 6-(2,2,2-Trifluoroethoxy)pyrazin-2-amine (CAS 1431654-74-8)
- 4-(2,2,2-Trifluoroethoxy)pyrimidin-5-amine (CAS 1443289-45-9)
Recommended Standards
- Niraparib Impurity 8 (CAS 1289174-44-2)
- 3-Methoxy-1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-amine (CAS 1006462-54-9)
- Tadalafil Impurity 131 (CAS 209120-51-4)
- 5-Methyl-6-nitro-[1,2,4]triazolo[1,5-a]pyrimidin-7(1H)-one (CAS 103778-83-2)
- (2S,5S)-Ethyl 5-vinylpyrrolidine-2-carboxylate (CAS 112009-97-9)
- NE 100 Hydrochloride (CAS 149409-57-4)
- 2-(methylsulfanyl)-4,5-dihydro-1H-imidazol-4-one hydroiodide (CAS 54855-80-0)
- 4-(2-(1h-Tetrazol-1-yl)acetyl)morpholine-3-carboxylic acid (CAS 1481870-83-0)
- Erythromycin thiocyanate impurity C reduced derivative (CAS CATO-C4X-100167)
- Alogliptin Impurity 8 (CAS 1820685-30-0)
- 4,6-Di(pyrrolidin-1-yl)-1,3,5-triazin-2-ol (CAS 37059-43-1)
- 3-(5-Chlorothiophen-2-yl)-4-methyl-1h-pyrazol-5-amine (CAS 1310741-30-0)
- 2-Amino-N-(4-fluorophenyl)-2-methylpropanamidehydrochloride (CAS 1219976-76-7)
- Insulin Degludec Impurity 7 (CAS CATO-C4X-21577)
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