1-(4-Nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid CAS 62160-87-6
| CAS No. | 62160-87-6 |
| Molecular Formula | C16H11N3O4 |
| Molecular Weight | 309.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid.
1-(4-Nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid (CAS 62160-87-6) is a high-purity analytical reference standard with the molecular formula C16H11N3O4 and a molecular weight of 309.28 g/mol.
The molecular framework of 1-(4-Nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid (C16H11N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(4-Nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11N3O4 |
| Molecular Weight | 309.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 3 |
Related Nitrophenyl Standards
- 1-(3-Nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid (CAS 62160-88-7)
- 3-(2-(3-Nitrophenyl)imidazo[1,2-a]pyridin-3-yl)acrylic acid (CAS 727652-20-2)
- 3-(2-(4-Nitrophenyl)imidazo[1,2-a]pyridin-3-yl)acrylic acid (CAS 820245-79-2)
- 3-(3-Nitrophenyl)-1-phenyl-1h-pyrazole-4-carboxylic acid (CAS 376358-93-9)
- 5-(2-Nitrophenyl)-N-(pyridin-3-yl)furan-2-carboxamide (CAS 332119-10-5)
- 3-(3-Nitrophenyl)-5-(1-phenylpropyl)-1,2,4-oxadiazole (CAS 433947-24-1)
- 3-(4-Nitrophenyl)-5-(1-phenylpropyl)-1,2,4-oxadiazole (CAS 434312-23-9)
- 4-Methyl-11-(4-nitrophenyl)-2,3,7,11-tetraazatricyclo[7.4.0.0^{2,6}]trideca-1(9),3,5,7-tetraene (CAS 866049-91-4)
Recommended Standards
- 1-(4-Methoxyphenyl)-3-((2,3,4-trifluorophenyl)amino)propan-1-one (CAS 868255-55-4)
- 1-Bromo-4-(trans-4-pentylcyclohexyl)benzene (CAS 79832-89-6)
- 2-({2-Amino-4-oxo-3H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}methyl)isoindole-1,3-dione (CAS 325488-82-2)
- (S)-2-((tert-butoxycarbonyl)amino)-2-(3-(trifluoromethyl)bicyclo[1.1.1]Pentan-1-yl)acetic acid (CAS 1986906-52-8)
- (4-(4-Nitrophenyl)piperazin-1-yl)(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)methanone (CAS 866154-42-9)
- 6-Cyclopropyl-1-methyl-3-oxo-1h,2h,3h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1087784-23-3)
- 5-Bromo-2-(2-fluorophenyl)-1H-indole (CAS 1188240-91-6)
- 5-(2-Cyclopentylethyl)-1,3,4-thiadiazol-2-amine (CAS 90769-34-9)
- 2,4,7-Trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidine-6-carboxylic acid (CAS 918476-94-5)
- Methyl 4-bromo-5-phenyl-1H-pyrazole-3-carboxylate (CAS 944941-49-5)
- 2,3-Dichloro-6-fluorobenzoic acid (CAS 32890-91-8)
- 5,7-Dichloro-4-nitro-2,1,3-benzoxadiazole (CAS 15944-78-2)
- N-(2-Morpholin-4-ylethyl)cyclopropanamine (CAS 1019442-93-3)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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