1-(Azidomethyl)-3,5-difluorobenzene CAS 622372-77-4
| CAS No. | 622372-77-4 |
| Molecular Formula | C7H5F2N3 |
| Molecular Weight | 169.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 169.13 g/mol gives 1-(Azidomethyl)-3,5-difluorobenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(Azidomethyl)-3,5-difluorobenzene (CAS 622372-77-4) is a high-purity analytical reference standard with the molecular formula C7H5F2N3 and a molecular weight of 169.13 g/mol.
Owing to a nitrile group, fluorine substitution, an aromatic ring system, 1-(Azidomethyl)-3,5-difluorobenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 169.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Azidomethyl)-3,5-difluorobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5F2N3 |
| Molecular Weight | 169.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Azidomethyl Standards
- 1-(Azidomethyl)-2,3-difluorobenzene (CAS 864528-03-0)
- 1-(azidomethyl)-2,4-difluorobenzene (CAS 622372-75-2)
- 5-(Azidomethyl)-2-chloropyridine (CAS 114780-17-5)
- 4-(azidomethyl)-2-ethyl-1,3-thiazole (CAS 1250225-58-1)
- 1365963-61-6 3-(Azidomethyl)-1,2,4-oxadiazole-5-carboxamide MFCD22056552 (CAS 1365963-61-6)
- 1-(azidomethyl)-3-chlorobenzene (CAS 126799-85-7)
- 1-(azidomethyl)-2-chlorobenzene (CAS 63777-70-8)
- 1-(Azidomethyl)-4-chlorobenzene (CAS 27032-10-6)
Recommended Standards
- 1-(difluoromethyl)-3-isocyanatobenzene (CAS 27181-22-2)
- 1-(Difluoromethyl)-4-isocyanatobenzene (CAS 76729-40-3)
- 1-(2-Methyl-5-nitrofuran-3-yl)ethanone (CAS 213469-81-9)
- 1,2-difluoro-4-(isocyanatomethyl)benzene (CAS 866538-73-0)
- 1H-Indazole-4-sulfonyl chloride (CAS 858227-51-7)
- (2E)-1-(3-Methoxyphenyl)-3-(5-methylthiophen-2-yl)prop-2-en-1-one (CAS 1287387-26-1)
- 3-Cyanopyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1558138-88-7)
- Tert-butyl 4-(2-amino-1-(4-fluorophenyl)ethyl)piperazine-1-carboxylate (CAS 1018297-04-5)
- 2-Bromo-4-cyclopropoxy-1-methoxybenzene (CAS 1243313-86-1)
- 2-(3-(Tetrahydrofuran-2-yl)-1,2,4-oxadiazol-5-yl)ethan-1-amine (CAS 1483295-31-3)
- 3-Chloro-5-methoxy-pyridine-2-carbonitrile (CAS 208994-06-3)
- Ethyl 2-Chloro-2-(methylimino)acetate (CAS 73188-60-0)
- 4-{2-[(5-chloro-2-methoxyphenyl)formamido]ethyl}benzene-1-sulfonyl chloride (CAS 33924-54-8)
- Acetyl-(Leu28·31)-Neuropeptide Y (24-36) (CAS 155709-24-3)
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