N-Benzyl-6-fluoro-7-(piperazin-1-yl)quinazolin-4-amine CAS 625080-59-3
| CAS No. | 625080-59-3 |
| Molecular Formula | C19H20FN5 |
| Molecular Weight | 337.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-Benzyl-6-fluoro-7-(piperazin-1-yl)quinazolin-4-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N-Benzyl-6-fluoro-7-(piperazin-1-yl)quinazolin-4-amine (CAS 625080-59-3), a certified reference material (molecular formula C19H20FN5, MW 337.39 g/mol) for analytical method development and quality control.
The molecular framework of N-Benzyl-6-fluoro-7-(piperazin-1-yl)quinazolin-4-amine (C19H20FN5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-Benzyl-6-fluoro-7-(piperazin-1-yl)quinazolin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H20FN5 |
| Molecular Weight | 337.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Recommended Standards
- N,N-Bis(2-bromoethyl)-9H-fluoren-2-amine (CAS 6036-92-6)
- O1-tert-butyl O2-methyl (2S,4R)-4-ethylsulfonyloxypyrrolidine-1,2-dicarboxylate (CAS 2387561-34-2)
- N-(2-(Hydroxymethyl)-4,5-dimethoxyphenyl)-4-methylbenzenesulfonamide (CAS 871563-17-6)
- rel-tert-Butyl (2R,4S)-2-((benzyloxy)methyl)-4-fluoro-2-formylpyrrolidine-1-carboxylate (CAS 2763156-92-7)
- 5-Formylpyridine-2-boronic acid, hydrate (CAS 1217500-70-3)
- 5-Nitro-2,3-dihydro-1H-inden-2-amine sulfate (CAS 370861-62-4)
- 8-Chloro-1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 99696-22-7)
- 2-(Cyclobutylamino)-N-(furan-2-ylmethyl)-2-thioxoacetamide (CAS 335373-66-5)
- 6-Chloro-7-cyclobutyl-3-(2,6-difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1351952-76-5)
- 1-[(oxiran-2-yl)methyl]pyrrolidin-2-one (CAS 17201-66-0)
- 1-Cyano-N,N,N-trimethylmethanaminium iodide (CAS 82272-28-4)
- 2-(4-(4-Chlorophenyl)-2-methyl-3-oxo-1,2,4-oxadiazolidin-5-yl)-N-(4-methylbenzyl)acetamide (CAS 478033-73-7)
- 1-(2-Methylcyclopropyl)propan-1-one (CAS 861543-58-0)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
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