3-(Trifluoromethyl)tetrahydro-4H-pyran-4-one CAS 625099-69-6
| CAS No. | 625099-69-6 |
| Molecular Formula | C6H7F3O2 |
| Molecular Weight | 168.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(Trifluoromethyl)tetrahydro-4H-pyran-4-one (CAS 625099-69-6) is a high-purity analytical reference standard with the molecular formula C6H7F3O2 and a molecular weight of 168.11 g/mol.
3-(Trifluoromethyl)tetrahydro-4H-pyran-4-one (C6H7F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7F3O2 |
| Molecular Weight | 168.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- 3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 1093750-93-6)
- cis-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 123812-82-8)
- trans-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 123812-83-9)
- 2-[1-(Trifluoromethyl)cyclopropyl]acetic Acid (CAS 1368342-07-7)
- 2-(trifluoromethyl)furan-3-carbaldehyde (CAS 1378259-70-1)
- 5-(trifluoromethyl)furan-2-carbaldehyde (CAS 17515-80-9)
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Recommended Standards
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- 2-Nitropyridine-4-carboxylic Acid (CAS 33225-74-0)
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- N-Isopropyl-2-phenylquinolin-4-amine dihydrochloride (CAS 853344-22-6)
- 2-(4-Bromo-6-(difluoromethyl)-5-(trifluoromethyl)pyridin-2-yl)acetonitrile (CAS 1806969-16-3)
- 5-((Tetrahydro-2H-pyran-4-yl)oxy)picolinic acid (CAS 1393330-58-9)
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