5-Fluoro-7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline CAS 625127-11-9

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

5-Fluoro-7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline (CAS 625127-11-9) is a high-purity analytical reference standard with the molecular formula C10H9F4N and a molecular weight of 219.18 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 5-Fluoro-7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

As a certified reference material (CRM), 5-Fluoro-7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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