5-(Trifluoromethoxy)benzo[d]thiazole CAS 876500-74-2
| CAS No. | 876500-74-2 |
| Molecular Formula | C8H4F3NOS |
| Molecular Weight | 219.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, 5-(Trifluoromethoxy)benzo[d]thiazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
5-(Trifluoromethoxy)benzo[d]thiazole (CAS 876500-74-2) is a high-purity analytical reference standard with the molecular formula C8H4F3NOS and a molecular weight of 219.18 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4F3NOS |
| Molecular Weight | 219.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Trifluoromethoxy Standards
- 2-(Trifluoromethoxy)phenyl isothiocyanate (CAS 175205-33-1)
- 4-(Trifluoromethoxy)phenyl Isothiocyanate (CAS 64285-95-6)
- 6-(Trifluoromethoxy)benzo[d]thiazole (CAS 876500-72-0)
- (R)-1-(3-(trifluoromethoxy)phenyl)propan-1-amine (CAS 1212933-09-9)
- (S)-1-(3-(trifluoromethoxy)phenyl)propan-1-amine (CAS 1213107-89-1)
- (R)-1-(4-(Trifluoromethoxy)phenyl)propan-1-amine (CAS 1213442-20-6)
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- 1-(4-(Trifluoromethoxy)phenyl)propan-1-amine, 97% (CAS 130339-50-3)
Recommended Standards
- 4-Aminophenylsulfur Pentafluoride (CAS 2993-24-0)
- 5-(Trifluoromethyl)benzo[d]thiazol-2(3H)-one, 97% (CAS 51550-10-8)
- 5-Fluoro-7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline (CAS 625127-11-9)
- 2,2,2-Trifluoro-N-(2-(methylsulfonyl)ethyl)acetamide (CAS 202197-68-0)
- tert-Butyl ((1R,2S)-1,3-dihydroxy-1-phenylpropan-2-yl)carbamate (CAS 183075-33-4)
- 2-(4-Fluorobenzylidene)malononitrile (CAS 2826-22-4)
- Ethyl 3-(4-iodo-3-methyl-1H-pyrazol-1-yl)propanoate (CAS 1354705-65-9)
- 1-MEthoxy-4-nitro-2-(propan-2-yloxy)benzene (CAS 36160-54-0)
- Nicardipine Impurity 47 (CAS 54527-65-0)
- Methyl 1-((4-bromophenyl)sulfonyl)-3-iodo-1H-indole-2-carboxylate (CAS 860611-95-6)
- 4-(2-Benzylphenoxy)aniline hydrochloride (CAS 1185297-18-0)
- 1-(5-(Ethylthio)-1,3,4-oxadiazol-2-yl)-2-phenylethan-1-amine (CAS 856436-81-2)
- Quinaldinesulfate (CAS 655-76-5)
- Hexapeptide-9 (CAS 1228371-11-6)
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