(S)-1-(4-Chlorobenzoyl)pyrrolidine-2-carboxylic acid CAS 62522-91-2
| CAS No. | 62522-91-2 |
| Molecular Formula | C12H12ClNO3 |
| Molecular Weight | 253.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (S)-1-(4-Chlorobenzoyl)pyrrolidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies (S)-1-(4-Chlorobenzoyl)pyrrolidine-2-carboxylic acid (CAS 62522-91-2), a certified reference material (molecular formula C12H12ClNO3, MW 253.68 g/mol) for analytical method development and quality control.
The molecular framework of (S)-1-(4-Chlorobenzoyl)pyrrolidine-2-carboxylic acid (C12H12ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H12ClNO3 |
| Molecular Weight | 253.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- 1-(3-Chlorobenzoyl)pyrrolidine-3-carboxylic acid (CAS 1274628-86-2)
- (2-Chlorobenzoyl)proline (CAS 672300-77-5)
- cis-2-(4-Chlorobenzoyl)cyclopentane-1-carboxylic acid (CAS 733740-14-2)
- trans-2-(3-Chlorobenzoyl)cyclopentane-1-carboxylic acid (CAS 733741-00-9)
- Ethyl (4-chlorobenzoyl)alaninate (CAS 1155848-58-0)
- (3-Chlorobenzoyl)valine (CAS 1396967-56-8)
- N-((4-chlorobenzoyl)oxy)pivalamide (CAS 64214-74-0)
- Methyl 2-[2-(2-Chlorobenzoyl)hydrazino]-2-oxoacetate (CAS 1956380-00-9)
Recommended Standards
- (S)-1-(4-Chlorobenzyl)-5-oxopyrrolidine-2-carboxylic acid (CAS 59749-22-3)
- (2-Chloro-6,7-dimethoxyquinolin-3-yl)methanol (CAS 92172-84-4)
- 1-(2-Chloro-4-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 63675-05-8)
- Ethyl 2-(5-chloro-7-methylimidazo[1,2-a]pyrimidin-2-yl)acetate (CAS 195072-95-8)
- Fmoc-<I>N</I>-Me-<SC>D</SC>-Phe-OH (CAS 138775-05-0)
- (S)-3-(4-Carbamoyl-2,6-dimethylphenyl)-2-methylpropanoic acid (CAS 1048677-16-2)
- 4-chloro-6-(chloromethyl)-2-(methylsulfanyl)pyrimidine (CAS 94694-53-8)
- 1,2-Ethanetricarboxylic acid, triethyl ester 1,2-Tricarbethoxyethane 7459-46-3 Ethane-1,2-tricarboxylic acid, triethyl ester NSC-78463 NSC78463 Triethyl ethane tricarboxylate Triethyl ethane-1,2-tricarboxylate (CAS 7459-46-3)
- 3-Acetamido-5-(trifluoromethyl)benzoic acid (CAS 500590-51-2)
- Methyl L-alanylglycinate hydrochloride (CAS 23404-09-3)
- bis(4-hydroxybutyl) furan-2,5-dicarboxylate (CAS CATO-C3D-262625)
- 5,7-dichlorofuro[3,2-b]pyridine (CAS 1936397-73-7)
- 4-Hydroxylidocaine (CAS 39942-41-1)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com