1-(2-Chloro-4-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid CAS 63675-05-8
| CAS No. | 63675-05-8 |
| Molecular Formula | C12H12ClNO3 |
| Molecular Weight | 253.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(2-Chloro-4-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(2-Chloro-4-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 63675-05-8), molecular formula C12H12ClNO3 and molecular weight 253.68 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-(2-Chloro-4-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid (C12H12ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 253.68 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2-Chloro-4-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12ClNO3 |
| Molecular Weight | 253.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- Ethyl 6-chloro-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 1035835-21-2)
- 3-Chloro-4-fluoro-N-(3-fluorobenzyl)aniline (CAS 1040309-97-4)
- 4-Chloro-2-fluoro-N-(2-fluorobenzyl)aniline (CAS 1152634-83-7)
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Recommended Standards
- (S)-1-(4-Chlorobenzyl)-5-oxopyrrolidine-2-carboxylic acid (CAS 59749-22-3)
- 1-(2-Chlorobenzyl)-5-oxoproline (CAS 87341-46-6)
- (S)-1-(4-Chlorobenzoyl)pyrrolidine-2-carboxylic acid (CAS 62522-91-2)
- 1-(3-Chloro-2-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 63674-94-2)
- (2-(4-Chloro-3-(trifluoromethyl)phenyl)benzo[d]oxazol-6-yl)methanol (CAS 820241-12-1)
- 3-(2,5-Dimethoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid (CAS 1283108-50-8)
- 2-(Methylsulfonamido)benzoic Acid (CAS 162787-61-3)
- Bz-DL-Arg-βNA · HCl (CAS 913-04-2)
- Methyl 4-amino-3,6-dichloropicolinate (CAS 350601-39-7)
- 1-(4-Hydroxy-1,5-dimethyl-1H-pyrazol-3-yl)ethanone (CAS 85985-64-4)
- 3,5-Difluoro-4-(1h-pyrazol-1-yl)benzaldehyde (CAS 1342028-33-4)
- Diethylene glycol diethyl ether (CAS 112-36-7)
- 2-Bromo-5-cyano-3-nitrobenzenesulfonyl chloride (CAS 1805581-81-0)
- Calcineurin Autoinhibitory Peptide (CAS 148067-21-4)
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