Methyl 6-amino-5-cyano-2-(((3-cyano-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)methyl)-4-(3-methoxyphenyl)-4H-pyran-3-carboxylate CAS 625369-17-7
| CAS No. | 625369-17-7 |
| Molecular Formula | C26H25N5O4S |
| Molecular Weight | 503.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 6-amino-5-cyano-2-(((3-cyano-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)methyl)-4-(3-methoxyphenyl)-4H-pyran-3-carboxylate is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 6-amino-5-cyano-2-(((3-cyano-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)methyl)-4-(3-methoxyphenyl)-4H-pyran-3-carboxylate (CAS 625369-17-7), molecular formula C26H25N5O4S and molecular weight 503.57 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 6-amino-5-cyano-2-(((3-cyano-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)methyl)-4-(3-methoxyphenyl)-4H-pyran-3-carboxylate (C26H25N5O4S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H25N5O4S |
| Molecular Weight | 503.57 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 3-Amino-6-(3,4-dimethoxyphenyl)-N-(4-methoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 625369-54-2)
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Recommended Standards
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