3-Amino-6-methyl-4-(thiophen-2-yl)-N-(4-(trifluoromethoxy)phenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide CAS 445382-88-7
| CAS No. | 445382-88-7 |
| Molecular Formula | C23H19F3N4O2S2 |
| Molecular Weight | 504.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 504.55 g/mol gives 3-Amino-6-methyl-4-(thiophen-2-yl)-N-(4-(trifluoromethoxy)phenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Amino-6-methyl-4-(thiophen-2-yl)-N-(4-(trifluoromethoxy)phenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide (CAS 445382-88-7), molecular formula C23H19F3N4O2S2 and molecular weight 504.55 g/mol, is a CATO reference standard with documented purity and traceability.
3-Amino-6-methyl-4-(thiophen-2-yl)-N-(4-(trifluoromethoxy)phenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide (C23H19F3N4O2S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Amino-6-methyl-4-(thiophen-2-yl)-N-(4-(trifluoromethoxy)phenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H19F3N4O2S2 |
| Molecular Weight | 504.55 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Amino Standards
- 2-Amino-4-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]-1-(1,3-dihydro-2H-isoindol-2-yl)-1,4-butaned (CAS 847928-32-9)
- Ethyl 6-amino-5-cyano-2-(((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)methyl)-4-(4-fluorophenyl)-4H-pyran-3-carboxylate (CAS 354556-46-0)
- Methyl 6-amino-5-cyano-2-(((3-cyano-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-yl)thio)methyl)-4-(4-fluorophenyl)-4H-pyran-3-carboxylate (CAS 354556-45-9)
- 3-Amino-N-(2,4-dimethylphenyl)-4-methylbenzamide (CAS 6370-19-0)
- 3-Amino-4-(2-chlorophenyl)-N-(4-chlorophenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 332372-56-2)
- 3-Amino-N-(2,3-dichlorophenyl)-4-phenyl-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 444153-42-8)
- 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one (CAS 1193165-26-2)
- 3-Amino-6-(3,4-dimethoxybenzyl)-N-(4-fluorophenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 939889-21-1)
Recommended Standards
- 2-((3-Cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(2-(trifluoromethoxy)phenyl)acetamide (CAS 488134-50-5)
- Vonoprazan Impurity 175 (CAS CATO-C4X-1020175)
- Fmoc-Gly-(Dmb)Gly-OH (CAS 848861-65-4)
- Vonoprazan Impurity 55 (CAS 2514957-29-8)
- 7-(Piperazin-1-yl)-1,2,3,4-tetrahydroisoquinoline (CAS 1260859-41-3)
- tert-Butyl 4-cyano-4-(pyridin-2-yl)piperidine-1-carboxylate (CAS 167263-04-9)
- Ethyl (2-chloro-6-ethoxy-4-formylphenoxy)acetate (CAS 6435-75-2)
- (R)-tert-butyl 3-(hydroxymethyl)morpholine-4-carboxylate (CAS 215917-99-0)
- 4, 4, 4- Trifluoro- 3- (trifluoromethyl) -1-butanol (CAS 17327-35-4)
- 2-Cyclopropoxy-1-iodo-3-(trifluoromethyl)benzene (CAS 1243468-92-9)
- N-benzylpiperidine-4-carboxamide (CAS 101264-48-6)
- Trichloro[1,1′-methylenebis[1,1-diphenylphosphine-κP]]oxorhenium (CAS 60260-17-5)
- 2-(Azetidin-3-yl)-5-methylpyrimidine (CAS 1237171-23-1)
- D-Ala35-Tirzepatide (CAS CATO-CPTD788904)
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