3-Amino-6-ethyl-N-(5-fluoro-2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide CAS 625370-68-5
| CAS No. | 625370-68-5 |
| Molecular Formula | C21H22FN3OS |
| Molecular Weight | 383.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Amino-6-ethyl-N-(5-fluoro-2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Amino-6-ethyl-N-(5-fluoro-2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 625370-68-5), molecular formula C21H22FN3OS and molecular weight 383.48 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Amino-6-ethyl-N-(5-fluoro-2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (C21H22FN3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Amino-6-ethyl-N-(5-fluoro-2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H22FN3OS |
| Molecular Weight | 383.48 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-6-ethyl-N-(3-fluoro-4-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 625370-20-9)
- 3-Amino-6-ethyl-N-(4-fluorobenzyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 445268-92-8)
- 2-((4-Amino-5-(3-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,6-dimethylphenyl)acetamide (CAS 763114-89-2)
- (2-Amino-1-(cyclohexylsulfonyl)-1H-benzo[d]imidazol-6-yl)(phenyl)methanone (CAS 63197-96-6)
- Propyl 3-(3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamido)benzoate (CAS 691866-89-4)
- 3-Amino-4,6-dimethyl-N-(4-(pentyloxy)phenyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 853743-67-6)
- 4-Amino-N-(4-(2-(4-methylpiperazin-1-yl)ethyl)phenyl)-3-nitrobenzamide (CAS 1206970-56-0)
- 2-Amino-7-methyl-5-oxo-6-phenethyl-4-phenyl-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile (CAS 265315-65-9)
Recommended Standards
- 4'-Cyano-[1,1'-biphenyl]-4-yl 4-hexylbenzoate (CAS 59443-81-1)
- 4-Methyl-N-[(1S)-1-methyl-2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]benzenesulfonamide (CAS 88129-44-6)
- 3-[1-Ethyl-2,2-bis(4-methoxyphenyl)vinyl]-1H-indole (CAS 354146-25-1)
- di-tert-Butyl 2-oxo-1,8,11-triazaspiro[5.6]dodecane-8,11-dicarboxylate (CAS 2007916-04-1)
- (R)-Trihexyphenidyl (CAS 40520-25-0)
- 5-(Aminomethyl)-4,6-dimethylpyridin-2-amine dihydrochloride (CAS 199296-47-4)
- 2-Phenyl-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridin-3-amine (CAS 1554457-93-0)
- (Z)-5-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)benzylidene)thiazolidine-2,4-dione (CAS 160596-25-8)
- N-(4-((7-chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-yl)amino)phenyl)acetamide (CAS 375837-77-7)
- 1-(1,2-Dimethyl-1h-imidazol-5-yl)methanamine (CAS 87786-09-2)
- 4-chloro-3-(5-cyclopropyl-1H-1,2,3,4-tetrazol-1-yl)aniline (CAS 1248147-57-0)
- 6-Bromo-4-chloro-1,3-benzothiazol-2-amine (CAS 81822-77-7)
- Oxohygrolidin (CAS 98813-11-7)
- Semaglutide Impurity 123 (CAS 71997-93-8)
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