2-((2-(3,4-Dihydroxyphenyl)-2-oxoethyl)thio)-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)nicotinonitrile CAS 625376-44-5
| CAS No. | 625376-44-5 |
| Molecular Formula | C23H17F3N2O5S |
| Molecular Weight | 490.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((2-(3,4-Dihydroxyphenyl)-2-oxoethyl)thio)-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)nicotinonitrile.
CATO supplies 2-((2-(3,4-Dihydroxyphenyl)-2-oxoethyl)thio)-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)nicotinonitrile (CAS 625376-44-5), a certified reference material (molecular formula C23H17F3N2O5S, MW 490.45 g/mol) for analytical method development and quality control.
The molecular framework of 2-((2-(3,4-Dihydroxyphenyl)-2-oxoethyl)thio)-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)nicotinonitrile (C23H17F3N2O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-((2-(3,4-Dihydroxyphenyl)-2-oxoethyl)thio)-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H17F3N2O5S |
| Molecular Weight | 490.45 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dihydroxyphenyl Standards
- 1-(3,4-Dihydroxyphenyl)-3-((2R,3R,4aR,6R,7S,8S,8aR)-2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-6-(hydroxymethyl)hexahydro-6H-pyrano[2,3-b][1,4]dioxin-3-yl)propan-1-one (CAS 229971-57-7)
- 3-(2,4-Dihydroxyphenyl)-3-(4-(dimethylamino)phenyl)isobenzofuran-1(3H)-one (CAS 6310-69-6)
- 4-(5-(3,5-dihydroxyphenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)benzamide (CAS CATO-C4X-218055)
- (2S)-2-(2,4-dihydroxyphenyl)-7-hydroxy-8-[(2R)-5-hydroxy-5-methyl-2-(prop-1-en-2-yl)hexyl]-5-methoxy-2,3-dihydro-4H-1-benzopyran-4-one 855746-98-4 CHEBI:81093 kurarinol (CAS 855746-98-4)
- (S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-6-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)chroman-4-one (CAS 118040-45-2)
- 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)chromenylium (CAS 47705-70-4)
- 4-(3,4-Dihydroxyphenyl)-7-hydroxy-5-(((3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-3-one (CAS 116329-89-6)
- (E)-3-(3,4-Dihydroxyphenyl)-1-(2-hydroxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)prop-2-en-1-one (CAS 499-29-6)
Recommended Standards
- (2R,3S)-2-(2,2-Bis(4-fluorophenyl)benzo[d][1,3]dioxol-5-yl)chromane-3,5,7-triol (CAS 89329-09-9)
- 2-((4-Allyl-5-(((3,4-dichlorophenyl)amino)methyl)-4H-1,2,4-triazol-3-yl)thio)-N-isopropyl-N-phenylacetamide (CAS 540498-20-2)
- (R)-4-((S)-1-Fluoroethyl)-3-(2-(((S)-1-(4-methyl-2'-(trifluoromethyl)-[3,4'-bipyridin]-6-yl)ethyl)amino)pyrimidin-4-yl)oxazolidin-2-one (CAS 1628805-46-8)
- Latamoxef Impurity 36 (CAS CATO-C4X-179836)
- tert-Butyl 7-chloro-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate (CAS 1421433-88-6)
- Guanidine-<SUP>15</SUP>N<SUB>3</SUB> hydrochloride (CAS 121616-39-5)
- (S)-Methyl 2-(pyrrolidin-2-yl)acetateHCl (CAS 259868-83-2)
- 2-Methyl-N-(pyrimidin-5-ylmethyl)butan-2-amine (CAS 1341305-42-7)
- 1-(4-Chloro-3-nitrophenyl)-3-(3-chlorophenyl)urea (CAS 574724-12-2)
- 3-(3,4-dichlorophenyl)propan-1-ol (CAS 39960-05-9)
- Ethyl 5-(benzyloxy)-1H-pyrrolo[2,3-c]pyridine-2-carboxylate (CAS 22754-90-1)
- Hept-6-enal (CAS 17206-61-0)
- Ticagrelor Impurity N33 (CAS 1345413-20-8)
- Des-Asp15-Tirzepatide (CAS CATO-CPTD788958)
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