2-((3-(2-Hydroxy-1H-benzo[d]imidazol-1-yl)propyl)thio)-6-(4-methoxyphenyl)-4-(trifluoromethyl)nicotinonitrile CAS 625376-42-3
| CAS No. | 625376-42-3 |
| Molecular Formula | C24H19F3N4O2S |
| Molecular Weight | 484.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-((3-(2-Hydroxy-1H-benzo[d]imidazol-1-yl)propyl)thio)-6-(4-methoxyphenyl)-4-(trifluoromethyl)nicotinonitrile (CAS 625376-42-3), a certified reference material (molecular formula C24H19F3N4O2S, MW 484.49 g/mol) for analytical method development and quality control.
The molecular framework of 2-((3-(2-Hydroxy-1H-benzo[d]imidazol-1-yl)propyl)thio)-6-(4-methoxyphenyl)-4-(trifluoromethyl)nicotinonitrile (C24H19F3N4O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2-((3-(2-Hydroxy-1H-benzo[d]imidazol-1-yl)propyl)thio)-6-(4-methoxyphenyl)-4-(trifluoromethyl)nicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H19F3N4O2S |
| Molecular Weight | 484.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Hydroxy Standards
- N-[6-(1-hydroxy-1-methyl-ethyl)-2-(2-methylsulfonylethyl)indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide (CAS 1931994-81-8)
- N-[6-(1-hydroxy-1-methyl-ethyl)-1-(2-methylsulfonylethyl)indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide (CAS 2751749-06-9)
- 2-Hydroxy-4-(6-(5-(4-methylbenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanamido)benzoic acid (CAS 613225-56-2)
- 3-Hydroxy-4-(4-isopropoxy-3-methylbenzoyl)-1-(3-morpholinopropyl)-5-(thiophen-2-yl)-1H-pyrrol-2(5H)-one (CAS 510712-19-3)
- n-(4-((4-(2-Hydroxy-3-(naphthalen-2-yloxy)propyl)piperazin-1-yl)sulfonyl)phenyl)acetamide (CAS 667891-33-0)
- N-(4-Hydroxy-3-(4-methylpiperazin-1-yl)phenyl)-2'-methyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)-[1,1'-biphenyl]-4-carboxamide (CAS 256227-77-7)
- 2-Hydroxy-4-{2-[5-oxo-3-phenyl-1-(4-phenyl-1,3-thiazol-2-yl)-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazino}benzoic acid (CAS 314761-11-0)
- Hydroxy Ebastine (CAS 210686-41-2)
Recommended Standards
- 2,6-Dimethoxyphenyl-6-O- b-D-glucopyranosyl b-D-Glucopyranoside (CAS 1416253-72-9)
- Mycophenolic Acid Sorbitol Ester (CAS CATO-C4X-212212)
- S-[2-(N7-Guanyl)ethyl]glutathione (CAS 100840-34-4)
- ((6-(Difluoromethyl)-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-1-yl)ethynyl)triisopropylsilane (CAS 2856022-12-1)
- 1,3-Dimethyl-5-{[4-(2-pyrazinyloxy)phenyl]methylene}-2,4,6(1H,3H,5H)-pyrimidinetrione (CAS 866156-95-8)
- [2-(aminomethyl)-1,3-thiazol-4-yl]methanol dihydrochloride (CAS 1607315-13-8)
- N-((4S)-4-methoxypyrrolidin-3-yl)-4-methylthiazole-5-carboxamide (CAS 1217989-02-0)
- 1-(3-fluoropropyl)piperazine dihydrochloride (CAS 1909316-97-7)
- 1-Allyl-5-methyl-1h-pyrazol-4-amine (CAS 1351386-72-5)
- rel-tert-Butyl (3R,4R)-4-amino-3-fluoropiperidine-1-carboxylate (CAS 907544-16-5)
- 5'-Bromo-4'-fluorospiro[cyclopropane-1,3'-indolin]-2'-one (CAS 913720-17-9)
- 3-Ethyl 2-methyl 4-methyl-1H-pyrrole-2,3-dicarboxylate (CAS 67855-96-3)
- Regadenoson Impurity 16 (CAS CATO-C4X-198516)
- Liraglutide(13-31)TFA Salt (CAS CATO-C4X-19929)
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