6-Cyclopropyl-2-{[2-(4-methylbenzenesulfonyl)ethyl]sulfanyl}-4-(trifluoromethyl)pyridine-3-carbonitrile CAS 625377-24-4
| CAS No. | 625377-24-4 |
| Molecular Formula | C19H17F3N2O2S2 |
| Molecular Weight | 426.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Cyclopropyl-2-{[2-(4-methylbenzenesulfonyl)ethyl]sulfanyl}-4-(trifluoromethyl)pyridine-3-carbonitrile (C19H17F3N2O2S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 6-Cyclopropyl-2-{[2-(4-methylbenzenesulfonyl)ethyl]sulfanyl}-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 625377-24-4), a certified reference material (molecular formula C19H17F3N2O2S2, MW 426.48 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Cyclopropyl-2-{[2-(4-methylbenzenesulfonyl)ethyl]sulfanyl}-4-(trifluoromethyl)pyridine-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H17F3N2O2S2 |
| Molecular Weight | 426.48 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Cyclopropyl Standards
- 1-Cyclopropyl-8-(difluoromethoxy)-7-(1-methylisoindolin-5-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 194804-72-3)
- (S)-1-Cyclopropyl-8-(difluoromethoxy)-7-(1-methylisoindolin-5-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 194804-76-7)
- 1-Cyclopropyl-6-fluoro-7-(3-((methylamino)methyl)pyrrolidin-1-yl)-4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 118829-06-4)
- 1-Cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 144634-02-6)
- 1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 182868-50-4)
- N-Cyclopropyl Bimatoprost (CAS 1138395-12-6)
- (S)-10-Cyclopropyl-1-(9H-fluoren-9-yl)-3,6-dioxo-2,9-dioxa-4,7-diazaundecan-11-oic acid (CAS 2414393-57-8)
- 10-Cyclopropyl-1-(9H-fluoren-9-yl)-3,6-dioxo-2,9-dioxa-4,7-diazaundecan-11-oic acid (CAS 2414254-47-8)
Recommended Standards
- 6-Amino-N-(4-methyl-1,3-thiazol-2-yl)-8-(trifluoromethyl)-4-thia-2-azatricyclo[7.5.0.0^{3,7}]tetradeca-1(9),2,5,7-tetraene-5-carboxamide (CAS 626227-60-9)
- Risperidone Impurity 29 (CAS 832747-55-4)
- 2-((3-Cyano-6-ethyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinolin-2-yl)thio)-N-(thiazol-2-yl)acetamide (CAS 664999-30-8)
- Risperidone Impurity 30 (CAS 1894509-66-0)
- 3-Bromo-9-propyl-9H-carbazole (CAS 865443-61-4)
- 1-((3-Fluoro-[1,1'-biphenyl]-4-yl)methyl)piperazine (CAS 1560837-36-6)
- (S)-tert-Butyl 3-(pyridin-2-yloxy)pyrrolidine-1-carboxylate (CAS 1224514-70-8)
- 2-(4-Methoxy-3-methylphenyl)indoline Hydrochloride (CAS 1177304-69-6)
- 3,5-Dichloro-2-(1,3-dioxolan-2-yl)pyrazine (CAS 1934593-51-7)
- Ethyl 2-(cyclopropylamino)-3-(1h-imidazol-1-yl)propanoate (CAS 1249929-29-0)
- 4-Propyl-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2h-1,4-benzoxazin-3-one (CAS 2377609-36-2)
- Montelukast EP Impurity A(Sodium Salt) (CAS 190078-45-6)
- 2-Phenylimidazo[2,1-a]isoquinoline (CAS 70845-68-0)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
Why CATO?
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