1-Cyclopropyl-8-(difluoromethoxy)-7-(1-methylisoindolin-5-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid CAS 194804-72-3
| CAS No. | 194804-72-3 |
| Molecular Formula | C23H20F2N2O4 |
| Molecular Weight | 426.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 1-Cyclopropyl-8-(difluoromethoxy)-7-(1-methylisoindolin-5-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
1-Cyclopropyl-8-(difluoromethoxy)-7-(1-methylisoindolin-5-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 194804-72-3), molecular formula C23H20F2N2O4 and molecular weight 426.41 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Cyclopropyl-8-(difluoromethoxy)-7-(1-methylisoindolin-5-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (C23H20F2N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H20F2N2O4 |
| Molecular Weight | 426.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Cyclopropyl Standards
- (S)-1-Cyclopropyl-8-(difluoromethoxy)-7-(1-methylisoindolin-5-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 194804-76-7)
- 6-Cyclopropyl-2-{[2-(4-methylbenzenesulfonyl)ethyl]sulfanyl}-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 625377-24-4)
- 1-Cyclopropyl-6-fluoro-7-(3-((methylamino)methyl)pyrrolidin-1-yl)-4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 118829-06-4)
- 1-Cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 144634-02-6)
- 1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 182868-50-4)
- N-Cyclopropyl Bimatoprost (CAS 1138395-12-6)
- (S)-10-Cyclopropyl-1-(9H-fluoren-9-yl)-3,6-dioxo-2,9-dioxa-4,7-diazaundecan-11-oic acid (CAS 2414393-57-8)
- 10-Cyclopropyl-1-(9H-fluoren-9-yl)-3,6-dioxo-2,9-dioxa-4,7-diazaundecan-11-oic acid (CAS 2414254-47-8)
Recommended Standards
- N-(4-(N-(4-(3-(Trifluoromethyl)phenoxy)but-2-yn-1-yl)sulfamoyl)phenyl)acetamide (CAS 1421482-29-2)
- 2-Hydroxy-5-((4-((4-sulfophenyl)diazenyl)phenyl)diazenyl)benzoic acid (CAS 25747-21-1)
- (2E,3E)-Ethyl 4-phenyl-2-(2-((2-(trifluoromethyl)phenyl)sulfonyl)hydrazono)but-3-enoate (CAS 2765851-64-5)
- 3-((Diphenoxyphosphoryl)oxy)benzyl butyrate (CAS 161179-36-8)
- 2-((5-(2-Bromophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(o-tolyl)acetamide (CAS 332388-15-5)
- 1-(Indolin-1-yl)-2-(methylamino)ethan-1-one hydrochloride (CAS 1049769-37-0)
- 2-(((1-Acetylpiperidin-4-yl)methyl)(cyclopropyl)amino)acetic acid (CAS 1353947-56-4)
- Nicergoline EP Impurity D (CAS 20826-04-4)
- Ticagrelor Impurity 3 (CAS 2096989-56-7)
- 1-(Benzo[d][1,3]dioxol-4-yl)butan-1-amine (CAS 1270471-38-9)
- (4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(2,6-dichloropyridin-3-yl)methanone (CAS 1023821-24-0)
- ivDde-Lys-OH (CAS 3033714-30-3)
- diisobutyl [1-[(ethoxycarbonyl)amino]-2,2,2-trifluoro-1-(trifluoromethyl)ethyl]phosphonate (CAS 330944-06-4)
- Antiarrhythmic peptide (cattle atrium) (CAS 81771-37-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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